ArticleJournal of diabetes investigation2022
Therapeutic effect of laparoscopic sleeve gastrectomy on obstructive sleep apnea and relationship of type 2 diabetes in Japanese patients with severe obesity.
Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- The impact of bariatric surgery on breathing-related polysomnography parameters-Updated systematic review and meta-analysis.Frontiers in sleep · 2023Pooled it
- Impact of laparoscopic sleeve gastrectomy on gut and oral microbiota diversity, weight loss, and the metabolic outcomes.Surgery today · 2026Article
- Long-term effects of sleeve gastrectomy on metabolic parameters and obstructive sleep apnea resolution: a prospective observational study.Sleep & breathing = Schlaf & Atmung · 2026Observational
- Reversal of Obesity-Related Spinal Epidural Lipomatosis after Metabolic and Bariatric Surgery: A Case Suggesting the Role of Ectopic Fat Reduction.Surgical case reports · 2026Article
- Anatomical Remodeling of the Upper Airway after Laparoscopic Sleeve Gastrectomy: A Multimodal Assessment of Structural and Functional Improvements in Obstructive Sleep Apnea.Obesity surgery · 2025Article
- Factors Affecting Histological Gastric Wall Thickness in Japanese Patients with Obesity.Obesity surgery · 2025Article
- Factors Associated with Persistent Obstructive Sleep Apnea After Bariatric Surgery: A Narrative Review.Nature and science of sleep · 2024Review
- Improvements of lung volumes and respiratory symptoms after weight loss through laparoscopic sleeve gastrectomy.Langenbeck's archives of surgery · 2022Article
- Therapeutic effect of laparoscopic sleeve gastrectomy on obstructive sleep apnea and relationship of type 2 diabetes in Japanese patients with severe obesity.Journal of diabetes investigation · 2022Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIMS/
introductionObstructive sleep apnea (OSA) is among the most important obesity-related diseases, and offers the potential for accelerated the early onset and progression of type 2 diabetes. The aim of the present study was to clarify the therapeutic effect of laparoscopic sleeve gastrectomy on OSA in severely obese Japanese patients, and to find correlations between OSA improvements and β-cell function (BCF). MATERIALS AND
methodsBetween September 2013 and December 2019, 61 patients who underwent laparoscopic sleeve gastrectomy were enrolled. The apnea-hypopnea index (AHI) was used to diagnose OSA. The tongue area, uvula area and other parameters were measured using cone-beam computed tomography. Regarding BCF parameters, the homeostasis model assessment of β-cell function, insulinogenic, Matsuda and disposition indexes were used to evaluate the improvement in BCF. Improvement of OSA was defined as AHI <15.
resultsThe improvement rate of OSA was 51.8% (29/56). The change in AHI was significantly correlated with the excess weight loss percentage (ρ = 0.501), changes in tongue area (ρ = 0.350) and uvula area (ρ = 0.341). Multivariate analysis showed that preoperative AHI and postoperative hemoglobin A1c were independent prognostic factors of OSA non-improvement. The homeostasis model assessment of β-cell function (P < 0.001), the insulinogenic index (P < 0.001) and the disposition index (P = 0.019) of patients with AHI of <15 were significantly higher than those in patients with AHI of ≥15.
conclusionsLaparoscopic sleeve gastrectomy is a promising procedure for severely obese patients with OSA. BCF recovery was found to be significantly higher in patients with OSA improvement.
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