Evidence map›Paper›PMID 35080130›Full record

ReviewThe clinical respiratory journal2022

Graft dysfunction and rejection of lung transplant, a review on diagnosis and management.

Haishuang Sun, Mei Deng, Wenhui Chen, Min Liu, Huaping Dai, Chen Wang

Abstract readReview
In one paragraph

Review in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Initial [European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Article
  8. Article
  9. Treatment Responses in Histologic Versus Molecular Diagnoses of Lung Rejection.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haishuang SunDepartment of Respiratory Medicine, The First Hospital of Jilin University, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0003-2403-7767
Mei DengChinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, China.
Wenhui ChenDepartment of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital; National Center for Respiratory Medicine; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; National Clinical Research Center for Respiratory Diseases, Beijing, China.
Min LiuDepartment of Radiology, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-1298-4441
Huaping DaiDepartment of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital; National Center for Respiratory Medicine; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; National Clinical Research Center for Respiratory Diseases, Beijing, China.ORCID https://orcid.org/0000-0003-1124-1582
Chen WangDepartment of Respiratory Medicine, The First Hospital of Jilin University, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0003-4723-5395

Funding

Chinese Academy of Medical SciencesNon-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2019PT320021Science and Technology Innovation in Medicine and Health Project 2018-I2M-1-0001
6 · The paper itself

Abstract

introductionLung transplantation has proven to be an effective treatment option for end-stage lung disease. However, early and late complications following transplantation remain significant causes of high mortality.

objectivesIn this review, we focus on the time of onset in primary graft dysfunction and rejection complications, as well as emphasize the role of imaging manifestations and pathological features in early diagnosis, thus assisting clinicians in the early detection and treatment of posttransplant complications and improving patient quality of life and survival. DATA SOURCE: We searched electronic databases such as PubMed, Web of Science, and EMBASE. We used the following search terms: lung transplantation complications, primary graft dysfunction, acute rejection, chronic lung allograft dysfunction, radiological findings, and diagnosis and treatment.

conclusionPrimary graft dysfunction, surgical complications, immune rejection, infections, and neoplasms represent major posttransplant complications. As the main posttransplant survival limitation, chronic lung allograft dysfunction has a characteristic imaging presentation; nevertheless, the clinical and imaging manifestations are often complex and overlap, so it is essential to understand the temporal evolution of these complications to narrow the differential diagnosis for early treatment to improve prognosis.

Indexed as

Lung TransplantationQuality of LifeGraft RejectionHumansLungTransplantation, Homologouschronic lung allograft dysfunctionlung transplantation complicationsprimary graft dysfunctionradiological findingstreatment

Identifiers

PMID35080130
PMCPMC9060084

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.