Evidence map›Paper›PMID 35080018›Full record

ArticleMedical physics2022

Automatic segmentation of high-risk clinical target volume for tandem-and-ovoids brachytherapy patients using an asymmetric dual-path convolutional neural network.

Yufeng Cao, April Vassantachart, Omar Ragab, Shelly Bian, Priya Mitra, Zhengzheng Xu, Audrey Zhuang Gallogly, Jing Cui, Zhilei Liu Shen, Salim Balik and 4 more

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Deep learning in MRI-guided radiation therapy: A systematic review.Journal of applied clinical medical physics · 2024
    Pooled it
  2. Review
  3. Systematic review of artificial intelligence in brachytherapy.Journal of contemporary brachytherapy · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. A review of artificial intelligence in brachytherapy.Journal of applied clinical medical physics · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Yufeng CaoDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
April VassantachartDepartment of Radiation Oncology, LAC+USC Medical Center, Los Angeles, California, USA.
Omar RagabDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Shelly BianDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Priya MitraDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Zhengzheng XuDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Audrey Zhuang GalloglyDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Jing CuiDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Zhilei Liu ShenDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Salim BalikDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Michael GribbleKeck School of Medicine, University of Southern California, Los Angeles, California, USA.
Eric L ChangDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Zhaoyang FanDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Wensha YangDepartment of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
University of Southern California · USLAC+USC Medical Center · US

Funding

Novel four dimensional magnetic resonance imaging to monitor pancreatic tumor infiltrating blood vessels and tumor response to chemoradiation therapyR21CA234637 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG, YANG, WENSHA · 2019 to 2020
$413k
NCI NIH HHS R21 CA234637NIH R21Act CA234637
6 · The paper itself

Abstract

purposesPreimplant diagnostic magnetic resonance imaging is the gold standard for image-guided tandem-and-ovoids (T&O) brachytherapy for cervical cancer. However, high dose rate brachytherapy planning is typically done on postimplant CT-based high-risk clinical target volume (HR-CTV

methodsPreimplant T2-weighted MR and postimplant CT images for 65 (48 for training, eight for validation, and nine for testing) patients were retrospectively solicited from our institutional database. MR was aligned to the corresponding CT using rigid registration. HR-CTV

resultsFor this patient cohort, the dual-path CNN model improved each of our objective findings, including DSC

conclusionsAn asymmetric CNN model with two encoding paths from preimplant MR (masked by HR-CTV

Indexed as

BrachytherapyFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeural Networks, ComputerRetrospective StudiesCNNDeep learningHDRhigh-risk CTVsegmentationTandem and Ovoids

Identifiers

PMID35080018
PMCPMC9170543
OpenAlexW4210372882

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.