Evidence map›Paper›PMID 35079472›Full record

ArticleNMC case report journal2021

Primary Central Nervous System T-cell Lymphoma as Methotrexate-associated Lymphoproliferative Disorders: Case Report.

Hiroto Kawano, Tomoaki Kitamura, Kazushi Higuchi, Kazuhiko Nozaki

Open access · diamondAbstract readCase Reports
In one paragraph

Article in NMC case report journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hiroto KawanoDepartment of Neurosurgery, Japanese Red Cross Nagahama Hospital, Nagahama, Shiga, Japan.
Tomoaki KitamuraDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
Kazushi HiguchiDepartment of Neurosurgery, Japanese Red Cross Nagahama Hospital, Nagahama, Shiga, Japan.
Kazuhiko NozakiDepartment of Neurosurgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
Nagahama City Hospital · JPShiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of primary central nervous system (CNS) lymphoma as methotrexate-associated lymphoproliferative disorders (MTX-LPD). A 75-year-old woman who had been treated for rheumatoid arthritis (RA) with MTX for 3 years was admitted to our hospital complaining of unsteady gait, nausea, and vomiting. T2-weighted image of magnetic resonance imaging (MRI) showed multiple high intensity mass-like lesions including right lateral, frontal and temporal lobes, and right cerebellar hemisphere. We performed surgical biopsy, and the pathological and immunohistochemical examinations identified T-cell lymphoma. The tumor regressed and the symptoms were resolved soon after MTX withdrawal. Primary CNS lymphoma due to MTX-LPD is a rare disease and only eight cases including ours are reported.

Indexed as

Epstein-Barr virusmethotrexate-associated lymphoproliferative disordersother iatrogenic immunodeficiency-associated lymphoproliferative disordersrheumatoid arthritisT-cell lymphoma

Identifiers

PMID35079472
PMCPMC8769407
OpenAlexW3173046341

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.