Evidence map›Paper›PMID 35079241›Full record

ArticleInternational journal of peptide research and therapeutics2022

Exploring Structural Mechanism of COVID-19 Treatment with Glutathione as a Potential Peptide Inhibitor to the Main Protease: Molecular Dynamics Simulation and MM/PBSA Free Energy Calculations Study.

Abderahmane Linani, Khedidja Benarous, Leila Bou-Salah, Mohamed Yousfi, Souraya Goumri-Said

Open access · bronzeAbstract read
In one paragraph

Article in International journal of peptide research and therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. Unveiling potent Schiff base derivatives with selective xanthine oxidase inhibition:Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  5. Article
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  7. Review
  8. Review
  9. Journal of molecular structure · 2022
    Article
  10. Article
  11. Review
  12. Review
  13. Potential of Natural Alkaloids From Jadwar (Frontiers in molecular biosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Abderahmane LinaniFundamental Sciences Laboratory, Amar Telidji University, Laghouat, Algeria.
Khedidja BenarousFundamental Sciences Laboratory, Amar Telidji University, Laghouat, Algeria.
Leila Bou-SalahFundamental Sciences Laboratory, Amar Telidji University, Laghouat, Algeria.
Mohamed YousfiFundamental Sciences Laboratory, Amar Telidji University, Laghouat, Algeria.
Souraya Goumri-SaidPhysics Department, College of Science, Alfaisal University, P.O. Box 50927, Riyadh, 11533 Saudi Arabia.ORCID 0000-0002-9333-7862
University of Laghouat · DZAlfaisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2019-novel coronavirus has unfolded everywhere in the world and obliged a billion human beings in open confinement, whereas many treatments, and vaccines have been proposed towards this pandemic. The main protease (M

Indexed as

COVID-19GlutathioneMain proteaseMM–PBSAMolecular dynamics simulationPeptide

Identifiers

PMID35079241
PMCPMC8777181
OpenAlexW4205917236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.