Evidence map›Paper›PMID 35079224›Full record

ArticleInternational medical case reports journal2022

Combined Central Retinal Artery and Vein Occlusion with Ischemic Optic Neuropathy After COVID-19 Vaccination.

Sol Lee, Kamalesh K Sankhala, Swaraj Bose, Ron P Gallemore

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  8. Retinal vascular occlusions in COVID-19 infection and vaccination: a literature review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
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  16. Retinal artery/vein occlusion complicating SARS-CoV-2 vaccinations.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sol LeeDepartment of Clinical Research, Retina Macula Institute, Torrance, CA, USA.
Kamalesh K SankhalaCedars-Sinai Medical Center, Beverly Hills, CA, USA.
Swaraj BoseNeuroOphthalmology & Orbital Surgery, Cedars-Sinai Medical Towers, NeuroEyeOrbit Institute, Los Angeles, CA, USA.
Ron P GallemoreDepartment of Clinical Research, Retina Macula Institute, Torrance, CA, USA.ORCID 0000-0002-6116-6026
Retina Macula Institute · USCedars-Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a case of combined central retinal vein and artery occlusion that evolved into ischemic optic neuropathy following the Pfizer COVID-19 vaccination.

methodsPatient was followed with optical coherence tomography (OCT), fluorescein angiography, and Humphrey visual field.

resultsPatient was able to recover vision from count fingers to 20/30 on a combination of aflibercept, steroidal and non-steroidal anti-inflammatories, a diuretic (acetazolamide), antiplatelet agents (aspirin and pentoxifylline), and an anticoagulant (apixaban).

conclusionCOVID-19 vaccination may be associated with a myriad of sight-threatening ocular thrombotic conditions, which may respond to a combination of anti-inflammatory and anticoagulant therapies.

Indexed as

COVID-19 vaccineNAIONPfizervascular thrombosis

Identifiers

PMID35079224
PMCPMC8778623
OpenAlexW4206322820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.