Evidence map›Paper›PMID 35079131›Full record

ArticleActa pharmacologica Sinica2022

Antidepressant-like effects of cinnamamide derivative M2 via D

Yan-Xin Che, Xiao-Yan Jin, Rong-Hua Xiao, Ming Zhang, Xiao-Hui Ma, Fei Guo, Yang Li

Open access · bronzeAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yan-Xin CheSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Xiao-Yan JinSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Rong-Hua XiaoSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ming ZhangCAS Key Laboratory of Receptor Research, Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Xiao-Hui MaState Key Laboratory of Core Technology in Innovative Chinese Medicine, Tasly Pharmaceutical Group Co., Ltd., Tianjin, 300410, China.
Fei GuoCAS Key Laboratory of Receptor Research, Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. guofei@simm.ac.cn.
Yang LiSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China. liyang@simm.ac.cn.
Nanjing University of Chinese Medicine · CNChinese Academy of Sciences · CNShanghai Institute of Materia Medica · CNTasly Holding Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depressive disorder is a global mental illness associated with severe mortality and disability. The dopaminergic system is involved in both the etiology and therapeutics of depression. Distinct functions of dopamine D

Indexed as

Major Depressive DisorderAnimalsAntidepressive AgentsCinnamatesDopamineDopamine AntagonistsMicePrefrontal CortexReceptors, Dopamine D1Receptors, Dopamine D2Antidepressive AgentscinnamamideCinnamatesDopamineDopamine AntagonistsReceptors, Dopamine D1Receptors, Dopamine D2D2 receptordepressionmedial prefrontal cortexmTORpyramidal neuronsTrkB

Identifiers

PMID35079131
PMCPMC9433382
OpenAlexW4210745274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.