Evidence map›Paper›PMID 35079073›Full record

ArticleScientific reports2022

Diagnostic and therapeutic characteristics of diabetes mellitus and risk of out-of-hospital cardiac arrest.

Jeong Ho Park, Young Sun Ro, Sang Do Shin, Kyoung-Chul Cha, Kyoung Jun Song, Sung Oh Hwang, phase II Cardiac Arrest Pursuit Trial with Unique Registry and Epidemiologic Surveillance (CAPTURES-II) investigators

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 13 institutions in 1 country.

Jeong Ho ParkDepartment of Emergency Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Korea.
Young Sun RoDepartment of Emergency Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Korea. Ro.youngsun@gmail.com.
Sang Do ShinDepartment of Emergency Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Korea.
Kyoung-Chul ChaDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Kyoung Jun SongLaboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, 101 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea.
Sung Oh HwangDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
phase II Cardiac Arrest Pursuit Trial with Unique Registry and Epidemiologic Surveillance (CAPTURES-II) investigators
Seoul National University Hospital · KRYonsei University · KRSeoul National University · KRAnsan University · KRAsan Medical Center · KRChonnam National University Hospital · KRChungbuk National University Hospital · KRChungnam National University Hospital · KRDankook University Hospital · KRHallym University Dongtan Sacred Heart Hospital · KRKorea University · KRSamsung Medical Center · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the risks of diabetes mellitus (DM) on out-of-hospital cardiac arrest (OHCA) and to investigate whether the risks of DM on OHCA varied according to the diagnostic and therapeutic characteristics of diabetes. We conducted a multicenter prospective case-control study in 17 University hospitals in Korea from September 2017 to December 2020. Cases were EMS-treated OHCA patients aged 20 to 79 with a presumed cardiac etiology. Community-based controls were recruited at a 1:2 ratio after matching for age, sex, and urbanization level of residence. A structured questionnaire and laboratory findings were collected from cases and controls. Multivariable conditional logistic regression analyses were conducted to estimate the risk of DM on OHCA by characteristics. A total of 772 OHCA cases and 1544 community-based controls were analyzed. A total of 242 (31.3%) OHCAs and 292 (18.9%) controls were previously diagnosed with DM. The proportions of type I DM (10.7% vs. 2.1%) and insulin therapy (15.3% vs. 6.5%) were higher in OHCAs with DM than in controls with DM. The duration of DM was longer in OHCAs than in controls (median 12 vs. 7 years). DM was associated with an increased risk of OHCA (aOR (95% CI), 2.13 (1.64-2.75)). Compared to the no diabetes group, the risks of OHCA increased in the diabetes patients with type I DM (5.26 (1.72-16.08)) and type II DM group (1.63 (1.18-2.27)), a long duration of DM prevalence (1.04 (1.02-1.06) per 1-year prevalence duration), and a high HbA1c level (1.38 (1.19-1.60) per 1% increase). By treatment modality, the aOR (95% CI) was lowest in the oral hypoglycemic agent (1.47 (1.08-2.01)) and highest in the insulin (6.63 (3.04-14.44)) groups. DM was associated with an increased risk of OHCA, and the risk magnitudes varied according to the diagnostic and therapeutic characteristics.

Indexed as

AdultAgedCase-Control StudiesDiabetes ComplicationsDiabetes MellitusFemaleHospitals, UniversityHumansMaleMiddle AgedOdds RatioOut-of-Hospital Cardiac ArrestProspective StudiesRepublic of KoreaRisk Factors

Identifiers

PMID35079073
PMCPMC8789864
OpenAlexW4210267529

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.