Evidence map›Paper›PMID 35079067›Full record

Observational studyScientific reports2022

Asthma in paediatric intensive care in England residents: observational study.

Mome Mukherjee, Steve Cunningham, Mohammad Romel Bhuia, Tsz-Yan Milly Lo, Jasper V Been, Aziz Sheikh

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Social inequalities in childhood asthma.The World Allergy Organization journal · 2024
    Review
  13. Article
  14. Place of death from asthma differs by age, race, and ethnicity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Article
  15. Routine FEVBreathe (Sheffield, England) · 2023
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mome MukherjeeAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK. mome.mukherjee@ed.ac.uk.
Steve CunninghamAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.
Mohammad Romel BhuiaAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.
Tsz-Yan Milly LoPaediatric Critical Care Unit, Royal Hospital for Children and Young People, Edinburgh, UK.
Jasper V BeenAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.
Aziz SheikhAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.

Funding

Asthma UK AUK-PG-2012-178British Heart FoundationChief Scientist OfficeDepartment of HealthMedical Research Council MC_PC_19004Medical Research Council MR/R004498/1Wellcome Trust
6 · The paper itself

Abstract

Despite high prevalence of asthma in children in the UK, there were no prior report on asthma admissions in paediatric intensive care units (PICU). We investigated the epidemiology and healthcare resource utilisation in children with asthma presenting to PICUs in England. PICANet, a UK national PICU database, was queried for asthma as the primary reason for admission, of children resident in England from April 2006 until March 2013. There were 2195 admissions to PICU for a median stay of 1.4 days. 59% were males and 51% aged 0-4 years. The fourth and fifth most deprived quintiles represented 61% (1329) admissions and 73% (11) of the 15 deaths. Deaths were most frequent in 10-14 years age (n = 11, 73%), with no deaths in less than 5 years age. 38% of admissions (828/2193) received invasive ventilation, which was more frequent with increasing deprivation (13% (108/828) in least deprived to 31% (260/828) in most deprived) and with decreasing age (0-4-year-olds: 49%, 409/828). This first multi-centre PICU study in England found that children from more deprived neighbourhoods represented the majority of asthma admissions, invasive ventilation and deaths in PICU. Children experiencing socioeconomic deprivation could benefit from enhanced asthma support in the community.

Indexed as

Intensive Care Units, PediatricPatient AdmissionAdolescentAsthmaChildChild, PreschoolCritical CareEnglandFemaleHospital MortalityHumansInfantInfant, NewbornMalePrevalenceProspective Studies

Identifiers

PMID35079067
PMCPMC8789863

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.