Evidence map›Paper›PMID 35078849›Full record

ArticleBMJ open2022

Impact of the COVID-19 pandemic on vaccine coverage for early childhood vaccines in Alberta, Canada: a population-based retrospective cohort study.

Shannon E MacDonald, Yuba Raj Paudel, Marilou Kiely, Ellen Rafferty, Manish Sadarangani, Joan L Robinson, S Michelle Driedger, Lawrence W Svenson, COVImm study team

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shannon E MacDonaldSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada smacdon@ualberta.ca.ORCID 0000-0003-4675-4433
Yuba Raj PaudelSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-3403-4359
Marilou KielyInstitut national de santé publique du Québec, Quebec, Quebec, Canada.
Ellen RaffertyFaculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Manish SadaranganiVaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Joan L RobinsonDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0001-9831-5681
S Michelle DriedgerDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Lawrence W SvensonAlberta Health, Government of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-3391-578X
COVImm study team
University of Alberta · CAInstitut National de Santé Publique du Québec · CAUniversity of British Columbia · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of the COVID-19 pandemic on early childhood vaccination coverage in Alberta, Canada.

settingAlberta, a western Canadian province, which has a population of 4.4 million and approximately 50 000 births annually.

designIn this retrospective cohort study, population-based administrative health data were analysed to determine the vaccination coverage for measles-containing, pertussis-containing and rotavirus vaccines. PRIMARY OUTCOME MEASURE: We measured monthly and cumulative vaccine coverage. We assessed the absolute difference in monthly and cumulative coverage for each vaccine dose by comparing children due for vaccination in each month of 2019 and 2020, with follow-up to determine if missed doses were caught up later.

participantsWe included 114 178 children in the 2019 analysis cohort and 106 530 children in the 2020 analysis cohort.

resultsMonthly vaccination coverage in 2020 was higher than 2019 until March, when coverage significantly declined. Comparing April 2020 to 2019, coverage was 9.9% (95% CI 7.9% to 12.0%) lower for measles vaccine; 4.9% (95% CI 3.3% to 6.5%), 7.1% (95% CI 5.2% to 9.1%), 5.2% (95% CI 3.1% to 7.4%) and 8.8% (95% CI 6.6% to 10.9%) lower for first, second, third and fourth doses of pertussis-containing vaccine, respectively; and 4.0% (95% CI 2.3% to 5.7%), 7.1% (95% CI 5.1% to 9.2%) and 4.6% (95% CI 2.4% to 6.7%) lower for first, second and third doses of rotavirus vaccine, respectively. Monthly coverage improved during May to July 2020; however, some doses experienced a second decline during September to October 2020. The cumulative coverage analysis showed that the measles-containing vaccine had the largest difference in coverage at the end of follow-up.

conclusionsChildren who were due for vaccination early in the pandemic and in Fall 2020, especially those due for measles vaccination, may require additional catch-up.

Indexed as

COVID-19PandemicsAlbertaChildChild, PreschoolCohort StudiesHumansInfantMeasles VaccineRetrospective StudiesSARS-CoV-2VaccinationMeasles VaccineCOVID-19epidemiologypaediatric infectious disease & immunisationpublic health

Identifiers

PMID35078849
PMCPMC8795926
OpenAlexW4207038957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.