Evidence map›Paper›PMID 35078844›Full record

ArticleBMJ open2022

Cohort profile: Alliance for Quality Assessment in Healthcare-Dialysis (AQuAH-D) prospective cohort study of patients on haemodialysis in Japan.

Sayaka Shimizu, Yoshihiro Onishi, Koji Kabaya, Jui Wang, Shingo Fukuma, Jun Morinaga, Shingo Hatakeyama, Shinya Kobayashi, Kazuyuki Maeno, Hajime Yamazaki and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Sayaka ShimizuDepartment of Research, Institute for Health Outcomes & Process Evaluation Research, Kyoto, Japan shimizu@i-hope.jp.ORCID 0000-0001-9283-144X
Yoshihiro OnishiDepartment of Research, Institute for Health Outcomes & Process Evaluation Research, Kyoto, Japan.
Koji KabayaDepartment of Research, Institute for Health Outcomes & Process Evaluation Research, Kyoto, Japan.
Jui WangDepartment of Research, Institute for Health Outcomes & Process Evaluation Research, Kyoto, Japan.
Shingo FukumaDepartment of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-8379-8761
Jun MorinagaDepartment of Nephrology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shingo HatakeyamaDepartment of Urology, Hirosaki University School of Medicine Graduate School of Medicine, Hirosaki, Japan.ORCID 0000-0002-0026-4079
Shinya KobayashiMiyanosawa Nephro-Urology Clinic, Hokkaido, Japan.
Kazuyuki MaenoJinyukai Hospital, Hokkaido, Japan.
Hajime YamazakiSection of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shunichi FukuharaSection of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kyoto University · JPFukushima Medical University · JPHirosaki University · JPKumamoto University · JPNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe global burden of kidney failure is increasing, but the treatment of kidney failure varies widely between patients, between dialysis facilities and over time. The Alliance for Quality Assessment in Healthcare-Dialysis (AQuAH-D) aims to conduct efficient and timely cohort studies on associations between those variations and clinical and patient-reported outcomes.

participantsIncluded are outpatients aged 20 years old or older who are undergoing haemodialysis and have consented to participate. A total of 2895 patients were enrolled from 25 facilities in Japan between August 2018 and July 2020 and are to be followed until 31 December 2026. Chart review and annual questionnaires are used to collect data on patient characteristics and on outcomes including quality of life. Data on medications, haemodialysis prescriptions and blood tests are obtained from existing electronic records. Data are collected retrospectively from 1 January 2017 to patient enrolment, and prospectively from patient enrolment until the end of December 2026. FINDINGS TO DATE: To date, the mean age is 68.3 (SD 12.2) years and 35.2% are female. The most common cause of kidney failure is diabetic nephropathy (37.4%). In January 2020, the facilities' median weekly doses of erythropoietin stimulating agent (ESA) and of intravenous vitamin D ranged from 1846 to 9692 IU (epoetin alfa equivalent) and 0.78 to 2.25 µg (calcitriol equivalent), respectively. The facilities' percentages of patients to whom calcimimetics are prescribed varied from 19% to 79%. During the retrospective period (averaging 1.85 years per participant), the incidence rates of any hospitalisation and of hospitalisation due to cardiovascular disease were 67.2 and 12.0 per 100 person-years, respectively. FUTURE PLANS: AQuAH-D data will be updated every 6 months and will be available for studies addressing a wide range of research questions, using the advantages of granular data and quality-of-life measurement of ageing patients on haemodialysis.

Indexed as

ErythropoietinKidney Failure, ChronicAdultAgedCohort StudiesDelivery of Health CareFemaleHumansJapanProspective StudiesQuality of LifeRenal DialysisRetrospective StudiesYoung AdultErythropoietindialysisepidemiologynephrology

Identifiers

PMID35078844
PMCPMC8796223
OpenAlexW4207007823

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.