Evidence map›Paper›PMID 35078723›Full record

ArticleTrends in parasitology2022

Protecting tissue integrity and enteric function: the case for type 2 inflammation and macrophages.

Qihua Ye, Barbara Balestrieri, Nora A Barrett

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qihua YeJeff and Penny Vinik Center for Translational Immunology Research, Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Barbara BalestrieriJeff and Penny Vinik Center for Translational Immunology Research, Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Nora A BarrettJeff and Penny Vinik Center for Translational Immunology Research, Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA. Electronic address: nbarrett@bwh.harvard.edu.
Brigham and Women's Hospital · US

Funding

Therapeutic Control of Aspirin-Exacerbated Respiratory DiseaseU19AI095219 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Maria Gutierrez-Arcelus · 2011 to 2026
$29.1M
IMMUNOLOGIC BASIS OF RESISTANCE AND HYPERSENSITIVITYT32AI007306 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Nora Amanda Barrett, Joshua A Boyce · 1985 to 2026
$12.2M
Type 2 Inflammation and Remodeling Elicited Through an LTE4/OXGR1-dependent pathwayR01AI134989 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Nora Amanda Barrett · 2019 to 2026
$5.1M
Allergic Pulmonary Inflammation Through the Dectin-2 PathwayR01HL120952 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BARRETT, NORA AMANDA · 2014 to 2018
$2.0M
Group VsPLA2 in Innate Immunity and Pulmonary InflammationR56HL113071 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BALESTRIERI, BARBARA · 2019 to 2019
$400k
Type 2 Mucosal Inflammation Elicited Through an LTE4/GPR99-Dependent PathwayR56AI134989 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BARRETT, NORA AMANDA · 2018 to 2018
$247k
NHLBI NIH HHS R01 HL120952NHLBI NIH HHS R56 HL113071NIAID NIH HHS R01 AI134989NIAID NIH HHS R56 AI134989NIAID NIH HHS T32 AI007306NIAID NIH HHS U19 AI095219NIH HHS U19 AI095219
6 · The paper itself

Abstract

Type 2 inflammation (T2I) accompanies many inflammatory diseases. In a recent issue of Cell, Ahrends et al. demonstrate that helminth-elicited T2I preserves excitatory neurons and enteric function through the expansion of Arginase-1 (Arg-1)-expressing macrophages, thereby extending our understanding of the protective functions that T2I can orchestrate in inflamed barrier tissue.

Indexed as

InflammationMacrophagesHumansalternatively activated macrophagesArginase-1type 2 inflammation

Identifiers

PMID35078723
PMCPMC11627152
OpenAlexW4207062260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.