ArticleBJPsych open2022
Investigating genetic overlaps of the genetic factor differentiating schizophrenia from bipolar disorder with cognitive function and hippocampal volume.
Article in BJPsych open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Five-factor personality traits in patients with schizophrenia and bipolar disorder: a systematic review and meta-analysis.The international journal of neuropsychopharmacology · 2025Pooled it
- Genetic predispositions for anxiety disorders and major depressive disorder affect current dietary habits in older patients with lifestyle-related diseases.The international journal of neuropsychopharmacology · 2026Article
- The Regulatory Potential of Long Non-Coding RNAs in Bipolar Disorder.International journal of molecular sciences · 2026Review
- Dissecting the shared genetic landscape of schizophrenia and hippocampal subfields: A genome-wide cross-trait analysis.Translational psychiatry · 2026Article
- Polygenic Risks for Mood Disorders and Economic Well-being: Study of Finnish Cohorts.Depression and anxiety · 2026Article
- Influences of genetic factors for educational attainment and cognitive functions on current dietary consumption.iScience · 2025Article
- Association of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging.Translational psychiatry · 2024Article
- Associations between Sjogren syndrome and psychiatric disorders in European populations: a 2-sample bidirectional Mendelian randomization study.Frontiers in psychiatry · 2024Article
- Psychiatric polygenic risk as a predictor of COVID-19 risk and severity: insight into the genetic overlap between schizophrenia and COVID-19.Translational psychiatry · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schizophrenia and bipolar disorder display clinical similarities and dissimilarities. We investigated whether the genetic factor differentiating schizophrenia from bipolar disorder is genetically associated with cognitive phenotypes and hippocampal volumes. We revealed genetic overlaps of the genetic differentiating factor with low general cognitive ability, low childhood IQ, low educational attainment and reduced hippocampal volumes. The genetic correlations with low general cognitive ability and reduced hippocampal volumes were associated with risk of schizophrenia, whereas the genetic correlations with high childhood IQ and educational attainment were associated with risks of bipolar disorder. These findings suggest these disorders have disorder-specific genetic factors related to clinical phenotypes.
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Registered trials
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