Evidence map›Paper›PMID 35078520›Full record

ArticleTrials2022

Pediatric Tuina in children with autism spectrum disorder: a study protocol for a randomized controlled trial.

Xiang Feng, Quanrui Jiang, Yuxing Zhang, Tao Li, Wei Wei, Jun Yu, Wu Li, Jiangshan Li

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiang FengSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Quanrui JiangSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Yuxing ZhangSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Tao LiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Wei WeiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Jun YuSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Wu LiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China.
Jiangshan LiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, 410208, Hunan, China. 001316@hnucm.edu.cn.ORCID http://orcid.org/0000-0001-8377-0497
Hunan University of Traditional Chinese Medicine · CN

Funding

Research and Development Program in Key Areas of Hunan Province 2019SK2081Research and Innovation Project for Graduate Students of Hunan Province CX2018B487Science and Technology Project of Changsha City kq1901093
6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is a neurodevelopmental condition characterized by repetitive stereotypical behavior and communication deficits. Currently, it lacks a specific clinical treatment method. Pediatric Tuina is a recent therapy in traditional Chinese medicine (TCM) and has been used to treat children with ASD. Nonetheless, it remains uncommon given the lack of large-scale evidence-based medical studies. This study aims to compare the efficacy of Tuina and conventional treatment in children with ASD.

methodsEligible children will be randomly assigned to either the pediatric Tuina plus conventional treatment group or to the conventional treatment alone group based on a random table at a ratio of 1:1. The effectiveness of the Tuina intervention for ASD will be evaluated by a third-party organization. The pre- and post-intervention scores on the Childhood Autism Rating Scale comprised the primary outcome, whereas pre- and post-intervention scores on the Autism Treatment Evaluation Checklist were the secondary outcomes to assess improvement in symptoms. Baseline values of the participants will be determined at the time of registration. Outcomes will be evaluated after the 30th treatment session. The follow-up period will last for 6 months after treatment. DISCUSSION: This study will evaluate the effectiveness and safety of Tuina in the treatment of ASD. The results of this study could provide reliable evidence to improve the management of patients with ASD.

trial registrationChinese Clinical Trial Registry (CHICTR), ChiCTR2000040452 . Registered on 28 November 2020.

Indexed as

Autism Spectrum DisorderAutistic DisorderChildHumansMedicine, Chinese TraditionalRandomized Controlled Trials as TopicTreatment OutcomeAutism spectrum disorderPediatric TuinaRandomized controlled trial

Identifiers

PMID35078520
PMCPMC8787946
OpenAlexW4225480837

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.