ArticleProceedings. Biological sciences2022
An unbiased test reveals no enrichment of sexually antagonistic polymorphisms on the human X chromosome.
Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- On the resolution of sexual conflict over shared traits.Proceedings. Biological sciences · 2024Review
- Polygenic response of sex chromosomes to sexual antagonism.Evolution; international journal of organic evolution · 2024Article
- Unveiling recent and ongoing adaptive selection in human populations.PLoS biology · 2024Article
- Patterns and evolutionary consequences of pleiotropy.Annual review of ecology, evolution, and systematics · 2023Article
- Slower-X: reduced efficiency of selection in the early stages of X chromosome evolution.Evolution letters · 2023Article
- An unbiased test reveals no enrichment of sexually antagonistic polymorphisms on the human X chromosome.Proceedings. Biological sciences · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Mutations with beneficial effects in one sex can have deleterious effects in the other. Such 'sexually antagonistic' (SA) variants contribute to variation in life-history traits and overall fitness, yet their genomic distribution is poorly resolved. Theory predicts that SA variants could be enriched on the X chromosome or autosomes, yet current empirical tests face two formidable challenges: (i) identifying SA selection in genomic data is difficult; and (ii) metrics of SA variation show persistent biases towards the X, even when SA variants are randomly distributed across the genome. Here, we present an unbiased test of the theory that SA variants are enriched on the X. We first develop models for reproductive
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.