Evidence map›Paper›PMID 35077878›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Severe Outcomes, Readmission, and Length of Stay Among COVID-19 Patients with Intellectual and Developmental Disabilities.

Alain K Koyama, Emilia H Koumans, Kanta Sircar, Amy Lavery, Joy Hsu, A Blythe Ryerson, David A Siegel

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Impact of the COVID-19 Pandemic on Autistic Adults: a Scoping Review.Current developmental disorders reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alain K KoyamaCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States. Electronic address: akoyama@cdc.gov.
Emilia H KoumansCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.
Kanta SircarCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.
Amy LaveryCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.
Joy HsuCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.
A Blythe RyersonCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.
David A SiegelCenters for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, 30341, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the association between intellectual and developmental disabilities (IDDs) and severe COVID-19 outcomes, 30-day readmission, and/or increased length of stay (LOS) using a large electronic administrative database.

methodsPatients hospitalized with COVID-19 were identified between March 2020 and June 2021 from more than 900 hospitals in the United States. IDDs included intellectual disability, cerebral palsy, Down syndrome, autism spectrum disorder (ASD), and other intellectual disabilities. Outcomes included intensive care unit (ICU) admission, invasive mechanical ventilation (IMV), 30-day readmission, mortality, and LOS.

resultsAmong 643,765 patients with COVID-19, multivariate models showed that patients with any IDD were at a significantly greater risk of at least 1 severe outcome, 30-day readmission, or longer LOS than patients without any IDD. Compared with those without any IDD, patients with Down syndrome had the greatest odds of ICU admission (odds ratio [OR] and 95% confidence interval [CI]: 1.96 [1.73-2.21]), IMV (OR: 2.37 [2.07-2.70]), and mortality (OR: 2.33 [2.00-2.73]). Patients with ASD and those with Down syndrome both had over a 40% longer mean LOS. Patients with intellectual disabilities had a 23% (12-35%) increased odds of 30-day readmission.

conclusionsResults suggest that patients hospitalized with COVID-19 with IDD have a significantly increased risk of severe outcomes, 30-day readmission, and longer LOS.

Indexed as

Autism Spectrum DisorderCOVID-19ChildDevelopmental DisabilitiesHumansLength of StayPatient ReadmissionSARS-CoV-2United StatesAutismCerebral palsyCOVID-19Developmental disorderDown syndromeIntellectual disability

Identifiers

PMID35077878
PMCPMC8783540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.