Evidence map›Paper›PMID 35077833›Full record

ArticleMicrobial pathogenesis2022

Increasing the frequency of omicron variant mutations boosts the immune response and may reduce the virus virulence.

Ali Adel Dawood

Abstract read
In one paragraph

Article in Microbial pathogenesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Cumulative effects of air pollution and climate drivers on COVID-19 multiwaves in Bucharest, Romania.Process safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B · 2022
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ali Adel DawoodMicrobiology, Department of Anatomy, College of Medicine, University of Mosul, Mosul, Iraq. Electronic address: aad@uomosul.edu.iq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus has posed a serious threat to the world since its discovery in Wuhan in 2019. Beta, gamma, delta, and the final omicron variants have emerged as a result of several mutations in the virion structure. The Australian Omicron S protein variant contains 37 mutations out of a total of 67 mutations. According to preliminary data from South Africa, Omicron variant infection is not associated with any particular symptoms. The purpose of this research was to determine how changes in the structure of the S protein alter the protein's interaction with the ACE2 receptor. The Omicron variant stimulates the immune response more than the wild strain.

Indexed as

COVID-19AustraliaHumansImmunityMutationSARS-CoV-2Spike Glycoprotein, CoronavirusVirulenceSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19MutationOmicronSARS-CoV-2Variant

Identifiers

PMID35077833
PMCPMC8783435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.