Evidence map›Paper›PMID 35077677›Full record

ArticleDevelopmental cell2022

Adaptive differentiation for fast barrier restoration.

Qiutan Yang, Prisca Liberali

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Qiutan YangFriedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland.
Prisca LiberaliFriedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland. Electronic address: prisca.liberali@fmi.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial regeneration can be mediated through activation of stem cells or de-differentiation of post-mitotic cells. In this issue of Developmental Cell, Ohara et al. report that regeneration of damaged intestinal villi occurs via a yes-associated protein 1 (YAP)-dependent adaptive differentiation of transit-amplifying progenitors to a fetal-like state that restores intestinal barrier function.

Indexed as

Intestinal MucosaStem CellsCell Differentiation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.