Evidence map›Paper›PMID 35076612›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Deep Learning Using Multiple Degrees of Maximum-Intensity Projection for PET/CT Image Classification in Breast Cancer.

Kanae Takahashi, Tomoyuki Fujioka, Jun Oyama, Mio Mori, Emi Yamaga, Yuka Yashima, Tomoki Imokawa, Atsushi Hayashi, Yu Kujiraoka, Junichi Tsuchiya and 3 more

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. A fuzzy fine-tuned model for COVID-19 diagnosis.Computers in biology and medicine · 2023
    Article
  11. Review
  12. Article
  13. A Feasibility Study on Proton Range Monitoring UsingTomography (Ann Arbor, Mich.) · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kanae TakahashiDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Tomoyuki FujiokaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-7141-8901
Jun OyamaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0003-4000-2142
Mio MoriDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-6107-4519
Emi YamagaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-5931-6507
Yuka YashimaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0001-9706-7145
Tomoki ImokawaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Atsushi HayashiDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Yu KujiraokaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Junichi TsuchiyaDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Goshi OdaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Tsuyoshi NakagawaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0003-1967-0445
Ukihide TateishiDepartment of Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning (DL) has become a remarkably powerful tool for image processing recently. However, the usefulness of DL in positron emission tomography (PET)/computed tomography (CT) for breast cancer (BC) has been insufficiently studied. This study investigated whether a DL model using images with multiple degrees of PET maximum-intensity projection (MIP) images contributes to increase diagnostic accuracy for PET/CT image classification in BC. We retrospectively gathered 400 images of 200 BC and 200 non-BC patients for training data. For each image, we obtained PET MIP images with four different degrees (0°, 30°, 60°, 90°) and made two DL models using Xception. One DL model diagnosed BC with only 0-degree MIP and the other used four different degrees. After training phases, our DL models analyzed test data including 50 BC and 50 non-BC patients. Five radiologists interpreted these test data. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated. Our 4-degree model, 0-degree model, and radiologists had a sensitivity of 96%, 82%, and 80-98% and a specificity of 80%, 88%, and 76-92%, respectively. Our 4-degree model had equal or better diagnostic performance compared with that of the radiologists (AUC = 0.936 and 0.872-0.967,

Indexed as

Breast NeoplasmsDeep LearningBreastFemaleHumansPositron Emission Tomography Computed TomographyRetrospective Studiesbreast cancerconvolutional neural networkdeep learningimage classificationPET

Identifiers

PMID35076612
PMCPMC8788419

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.