Evidence map›Paper›PMID 35076502›Full record

ArticleClinics and practice2022

Plasma Rich in Growth Factors in Macular Hole Surgery.

Ronald M Sánchez-Ávila, Carlos A Robayo-Esper, Eva Villota-Deleu, Álvaro Fernández-Vega Sanz, Álvaro Fernández-Vega González, Borja de la Sen-Corcuera, Eduardo Anitua, Jesús Merayo-Lloves

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Clinics and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06323902 (Clinical Evidence of Autologous Platelet-Rich Plasma as a Treatment for Macular Holes), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06323902 completednot on this map

Clinical Evidence of Autologous Platelet-Rich Plasma as a Treatment for Macular Holes

TypeobservationalSponsorClinica Oftalmologica ParedesRan2022 to 2024Enrolled13ConditionsMacular Holes, Macular Hole of Left Eye (Disorder), Macular Hole of Right Eye (Disorder)ArmsPars plana vitrectomy, with or without epiretinal membrane peeling, plus PRGF membrane implantation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Platelet concentrates in macular hole surgery. A journey through the labyrinth of terminology, preparation, and application: a comprehensive review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ronald M Sánchez-ÁvilaOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.ORCID 0000-0002-5884-6741
Carlos A Robayo-EsperOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.
Eva Villota-DeleuOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.
Álvaro Fernández-Vega SanzOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.
Álvaro Fernández-Vega GonzálezOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.ORCID 0000-0002-9104-7917
Borja de la Sen-CorcueraRegenerative Medicine Laboratory, Biotechnology Institute (BTI), 01007 Vitoria, Spain.ORCID 0000-0001-9779-879X
Eduardo AnituaRegenerative Medicine Laboratory, Biotechnology Institute (BTI), 01007 Vitoria, Spain.
Jesús Merayo-LlovesOphthalmology Research Foundation, Fernández-Vega University Institute, University of Oviedo, 33071 Oviedo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the use of PRGF (plasma rich in growth factors) as an adjuvant to PPV (pars plana vitrectomy) in recurrent, persistent, or poor prognosis MH (macular hole). Patients with MH were treated with PPV plus adjuvant therapy (PRGF membrane (mPRGF) and injectable liquid PRGF (iPRGF)). The anatomical closure of MH and postoperative BCVA (best-corrected visual acuity) were evaluated. Eight eyes (eight patients) were evaluated: myopic MH (MMH,

Indexed as

macular holemacular hole surgeryoptical coherence tomographyPRGFretinal regeneration

Identifiers

PMID35076502
PMCPMC8788286

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.