Evidence map›Paper›PMID 35076395›Full record

ArticleeLife2022

A genetic compensatory mechanism regulated by

Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco, Juana Gallar, Peter Arthur-Farraj, Jose A Gomez-Sanchez, Hugo Cabedo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Molecular and Biological Function of MEF2D in Leukemia.Advances in experimental medicine and biology · 2024
    Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 4 countries.

Sergio Velasco-Aviles *Instituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-9672-2264
Nikiben Patel *Instituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-0129-7622
Angeles Casillas-BajoInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.
Laura Frutos-RincónInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-0768-3735
Enrique VelascoInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0001-7299-0750
Juana GallarInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-3559-3649
Peter Arthur-FarrajJohn Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0002-1239-9392
Jose A Gomez-SanchezInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-6746-1800
Hugo CabedoInstituto de Neurociencias de Alicante UMH-CSIC, Alicante, Spain.ORCID https://orcid.org/0000-0002-1322-6290
Instituto de Neurociencias · ESUniversity of Cambridge · GB

Funding

Wellcome Trust 206634/Z/17/Z
6 · The paper itself

Abstract

The class IIa histone deacetylases (HDACs) have pivotal roles in the development of different tissues. Of this family, Schwann cells express

Indexed as

RemyelinationAnimalsFemaleGene Expression RegulationGenes, junHistone DeacetylasesMaleMEF2 Transcription FactorsMicePeripheral NervesSchwann CellsHistone DeacetylasesMef2d protein, mouseMEF2 Transcription Factorscell biologyclass II HDACsgene compensationmousemyelinnerve developmentnerve regenerationneuroscienceratSchwann cells

Identifiers

PMID35076395
PMCPMC8853665
OpenAlexW4210294783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.