ArticleAustralian veterinary journal2022
Emerging leptospirosis in urban Sydney dogs: a case series (2017-2020).
Article in Australian veterinary journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of the prevalence of environmental and host-related risk factors and the zoonotic potential of leptospirosis in domestic dogs in regions impacted by environmental changes.BMC veterinary research · 2025Pooled it
- Longitudinal Survey of Pathogenic Leptospira Species at a Major Park in Sydney, Australia.EcoHealth · 2026Article
- Clinical and molecular characterization of an outbreak of leptospirosis in dogs from Los Angeles County, California, USA, 2021.Journal of clinical microbiology · 2026Article
- Emerging human and canine leptospirosis in New South Wales: insights from a One Health geospatial study.Science in One Health · 2025Article
- Survival outcomes, low awareness, and the challenge of neglected leptospirosis in dogs.Open veterinary journal · 2024Article
- Are PathogenicTropical medicine and infectious disease · 2024Article
- Landscape, Socioeconomic, and Meteorological Risk Factors for Canine Leptospirosis in Urban Sydney (2017-2023): A Spatial and Temporal Study.Veterinary sciences · 2023Article
- Developing diagnostic tools for canine periodontitis: combining molecular techniques and machine learning models.BMC veterinary research · 2023Article
- PathogenicMicroorganisms · 2023Article
- Emerging canine leptospirosis in Sydney and the role of population demographics.Transboundary and emerging diseases · 2022Article
- Emerging leptospirosis in urban Sydney dogs: a case series (2017-2020).Australian veterinary journal · 2022Article
- Leptospirosis is an emerging infectious disease of pig-hunting dogs and humans in North Queensland.PLoS neglected tropical diseases · 2022Article
- Updated ACVIM consensus statement on leptospirosis in dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Canine leptospirosis has not been reported in the Sydney dog population since 1976. However, between 2017 and 2020, leptospirosis was confirmed in 17 dogs, five of which were known to hunt rodents. Dogs infected between 2017 and 2019 lived within a 3 km radius in the Inner City of Sydney (n = 11). In 2020, cases emerged across a broader area of Sydney; Inner City (n = 1), Inner West (n = 3), Lower North Shore (n = 1) and Upper North Shore (n = 1). The disease was characterised by severe hepatorenal involvement resulting in an unusually high case fatality rate (88%). In conjunction with supportive clinical signs, diagnosis was confirmed by real-time PCR on whole blood (n = 1), kidney (n = 1), urine (n = 4), whole blood and urine (n = 9) or by seroconversion (n = 3). Antibody titres determined by Microscopic Agglutination Test (MAT) to Leptospira serovars were measured in 12 dogs: seven were positive for serovar Copenhageni, one was positive for serovar Hardjo, three were negative for all serovars, likely due to insufficient time for seroconversion before death and one had a low positive titre (1/50) for serovars Australis and Robinsoni. This sudden emergence of a highly fatal disease in pet dogs in Sydney has led to the introduction of Leptospira vaccination protocols for dogs living in inner Sydney using a monovalent vaccine containing serovar Copenhageni. The success of this vaccination program will require ongoing research to understand the emergence of leptospirosis in this region and the serovars involved.
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