ArticleeLife2022
Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health.
Open access · goldAbstract readMulticenter Study
In one paragraph
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children.Clinical epigenetics · 2025Pooled it
- Association of three different dietary patterns with the metabolomic profiles of children: the BiomarKid project.European journal of nutrition · 2026Article
- Association Between Habitual Dietary Intake and Urinary Metabolites in Adults-Results of a Population-Based Study.Metabolites · 2025Article
- Dietary patterns among European children and their association with adiposity-related outcomes: a multi-country study.International journal of obesity (2005) · 2025Article
- Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Association of Ultraprocessed Foods Intake with Untargeted Metabolomics Profiles in Adolescents and Young Adults in the DONALD Cohort Study.The Journal of nutrition · 2024Article
- Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease.Scientific reports · 2024Article
- Changes in urinary metabolomic profile show the effectiveness of a nutritional intervention in children 6-12 years old: The ALINFA study.Food science & nutrition · 2024Article
- Article
- Circulating metabolites modulated by diet are associated with depression.Molecular psychiatry · 2023Article
- Article
- Altered dietary behaviour during pregnancy impacts systemic metabolic phenotypes.Frontiers in nutrition · 2023Article
- Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing.Frontiers in nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors at 13 institutions in 12 countries.
Nikos Stratakis *Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.ORCID 0000-0003-4613-0989
Alexandros P Siskos *Cancer Metabolism & Systems Toxicology Group, Division of Cancer, Department of Surgery & Cancer and Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.ORCID 0000-0002-5635-7426
Eleni Papadopoulou *Norwegian Institute of Public Health, Oslo, Norway.
Anh N NguyenDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Yinqi ZhaoDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Katerina MargetakiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Chung-Ho E LauCancer Metabolism & Systems Toxicology Group, Division of Cancer, Department of Surgery & Cancer and Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Muireann CoenCancer Metabolism & Systems Toxicology Group, Division of Cancer, Department of Surgery & Cancer and Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Lea MaitreISGlobal, Barcelona, Spain.
Silvia Fernández-BarrésISGlobal, Barcelona, Spain.
Lydiane AgierInserm, CNRS, University Grenoble Alpes, Team of environmental epidemiology applied to reproduction and respiratory health, IAB, Grenoble, France.
Sandra AndrusaityteDepartment of Environmental Sciences, Vytautas Magnus University, Kaunas, Lithuania.
Xavier BasagañaISGlobal, Barcelona, Spain.
Anne Lise BrantsaeterNorwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0001-6315-7134
Maribel CasasISGlobal, Barcelona, Spain.
Serena FossatiISGlobal, Barcelona, Spain.
Regina GrazulevicieneDepartment of Environmental Sciences, Vytautas Magnus University, Kaunas, Lithuania.
Barbara HeudeCentre for Research in Epidemiology and Statistics, Université de Paris, Inserm, Inra, Paris, France.
Rosemary Rc McEachanBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom.
Helle Margrete MeltzerNorwegian Institute of Public Health, Oslo, Norway.
Christopher MillettPublic Health Policy Evaluation Unit, School of Public Health, Imperial College, London, United Kingdom.
Fernanda RauberPublic Health Policy Evaluation Unit, School of Public Health, Imperial College, London, United Kingdom.
Oliver RobinsonMRC Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom.
Theano RoumeliotakiDepartment of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Eva BorrasISGlobal, Barcelona, Spain.
Eduard SabidóISGlobal, Barcelona, Spain.
Jose UrquizaISGlobal, Barcelona, Spain.
Marina VafeiadiDepartment of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Paolo VineisMRC Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom.
Trudy VoortmanDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.
John WrightBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom.
David V ContiDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Martine VrijheidISGlobal, Barcelona, Spain.
Hector C Keun *Cancer Metabolism & Systems Toxicology Group, Division of Cancer, Department of Surgery & Cancer and Division of Systems Medicine, Department of Metabolism, Digestion & Reproduction, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Leda Chatzi *Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Universitat Pompeu Fabra · ESUniversity of Southern California · USHammersmith Hospital · GBNorwegian Institute of Public Health · NOBradford Teaching Hospitals NHS Foundation Trust · GBCentre for Genomic Regulation · ESErasmus MC · NLImperial College London · GBUniversidade de São Paulo · BRUniversity of Crete · GRVytautas Magnus University · LTCentre National de la Recherche Scientifique · FRInserm · FR
Funding
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4MStatistical Methods for Integrative Genomics in CancerP01CA196569 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Paul Marjoram · 2016 to 2026
$25.5MUSC RESEARCH CENTER FOR LIVER DISEASES: PILOT PROGRAMSP30DK048522 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OOKHTENS, MURAD · 1995 to 2020
$21.8MEffects of DDE exposure on adipose tissue function, weight loss and metabolic improvement after bariatric surgery: A new paradigm for study of lipophilic chemicalsR01ES030364 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHATZI, VAIA LIDA · 2020 to 2024
$3.2MEnvironmental Chemical Exposures and Longitudinal Changes of Glucose Metabolism, Insulin Sensitivity and B Cell Function in YouthR01ES029944 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHATZI, VAIA LIDA · 2019 to 2023
$3.1MIncorporating intermediate biomarkers of folate with colorectal cancerR01CA140561 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CONTI, DAVID V, SCHUMACHER, FREDRICK RAY · 2011 to 2015
$1.9MHepatotoxic effects of perfluoroalkyl substances: a new epidemiological approach for studying environmental fatty liver diseaseR01ES030691 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHATZI, VAIA LIDA · 2020 to 2022
$1.9MHIERARCHICAL MODELING OF INTERACTIONS IN GENOME-WIDE AND PATHWAY-BASED STUDIESR01ES016813 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CONTI, DAVID V · 2009 to 2010
$1.1MThe adipose exposome effects on the plasma metabolome, body composition and metabolic outcomes after bariatric surgeryR21ES028903 · NIEHS · EMORY UNIVERSITY · PI CHATZI, VAIA LIDA, ZIEGLER, THOMAS R · 2018 to 2019
$455kDevelopmental origins of child liver injury: Effects of prenatal environmental exposuresR21ES029681 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHATZI, VAIA LIDA · 2019 to 2020
$453kDepartment of HealthMedical Research Council MR/S03532X/1NCI NIH HHS P01 CA196569NCI NIH HHS R01 CA140561NIDDK NIH HHS P30 DK048522NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R01 ES016813NIEHS NIH HHS R01 ES029944NIEHS NIH HHS R01 ES030364NIEHS NIH HHS R01 ES030691NIEHS NIH HHS R21 ES028903NIEHS NIH HHS R21 ES029681Wellcome TrustWellcome Trust 101597
Abstract
Urinary metabolic profiling is a promising powerful tool to reflect dietary intake and can help understand metabolic alterations in response to diet quality. Here, we used
Indexed as
DietMetabolomeBiomarkersChildDiet, MediterraneanEuropeFemaleHumansMagnetic Resonance SpectroscopyMaleMetabolomicsRegression AnalysisROC CurveBiomarkersepidemiologyeuropean childrenglobal healthhumanmediterranean diet adherencemetabolomicsNMR spectroscopyultra-processed food intake
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.