Evidence map›Paper›PMID 35076004›Full record

ArticleEmerging infectious diseases2022

Epidemiology of Hospitalized Patients with Babesiosis, United States, 2010-2016.

Evan M Bloch, Jonathan R Day, Peter J Krause, Anne Kjemtrup, Sheila F O'Brien, Aaron A R Tobian, Ruchika Goel

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Mapping the Global Distribution ofTransboundary and emerging diseases · 2025
    Pooled it
  2. CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria - United States, 2026.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2026
    Article
  3. Article
  4. Urban surveillance ofFrontiers in veterinary science · 2026
    Article
  5. Article
  6. Article
  7. Human babesiosis: The past, present and future.Expert reviews in molecular medicine · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Survey forInternational journal for parasitology. Parasites and wildlife · 2024
    Article
  12. Beyond Human Babesiosis: Prevalence and Association ofOpen forum infectious diseases · 2024
    Article
  13. Article
  14. Review
  15. Transfusion-transmittedJournal of clinical microbiology · 2023
    Review
  16. Molecular Screening of Blood Donors forTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  17. Review
  18. Reduced Cholesterol Levels during Acute Human Babesiosis.Pathogens (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Serum metabolomic profiles in BALB/c mice induced byFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Evan M Bloch
Jonathan R Day
Peter J Krause
Anne Kjemtrup
Sheila F O'Brien
Aaron A R Tobian
Ruchika Goel
Canadian Blood Services · CAJohns Hopkins University · USCalifornia Department of Public Health · USJohns Hopkins Medicine · USUniversity of Iowa Health Care · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Pathology CoreP01HL152960 · NHLBI · UNIVERSITY OF IOWA · PI STOLTZ, DAVID A · 2020 to 2024
$11.6M
Iowa StARR Scholars ProgramR38HL150208 · NHLBI · UNIVERSITY OF IOWA · PI PAUL B MCCRAY, DAVID A STOLTZ · 2021 to 2026
$1.5M
The Malaria Transfusion Risk (MATRix) StudyK23HL151826 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BLOCH, EVAN MARTIN · 2020 to 2024
$882k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL151826NHLBI NIH HHS P01 HL152960NHLBI NIH HHS R38 HL150208
6 · The paper itself

Abstract

Babesia spp. are tickborne parasites that cause the clinical infection babesiosis, which has an increasing incidence in the United States. We performed an analysis of hospitalizations in the United States during 2010-2016 in which babesiosis was listed as a diagnosis. We used the National Inpatient Sample database to characterize the epidemiology of Babesia-associated admissions, reflecting severe Babesia-related disease. Over a 7-year period, a total of 7,818 hospitalizations listed babesiosis as a primary or secondary admitting diagnosis. Hospitalizations were seasonal (71.2% occurred during June-August) and situated overwhelmingly in the Northeast and Midwest. The patients were predominantly male and of advanced age, which is consistent with the expected epidemiology. Despite a higher severity of illness in more than (58.5%), the mortality rate was low (1.6%). Comparison with state reporting data suggests that the number of hospitalized persons with babesiosis increased modestly during the observation period.

Indexed as

BabesiaBabesiosisDatabases, FactualHospitalizationHumansInpatientsMaleUnited StatesBabesiababesiosisepidemiologyhospitalizationparasitesticksUnited Statesvector-borne infections

Identifiers

PMID35076004
PMCPMC8798708
OpenAlexW4210677908

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.