ArticleJournal of Korean medical science2022
Clinical Characteristics of Atopic Dermatitis in Korean School-Aged Children and Adolescents According to Onset Age and Severity.
Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 19 citations in OpenAlex.
- Factors associated with the health-related quality of life of adolescents with atopic dermatitis in South Korea: a cross-sectional study.Child health nursing research · 2026Article
- A Multicenter Cross-Sectional Study on Clinical Characteristics and Disease Burden of 1010 Patients with Moderate to Severe Atopic Dermatitis in Chinese Tertiary Hospitals.Clinical, cosmetic and investigational dermatology · 2026Article
- Clinical Validation of the Updated Korean Atopic Dermatitis Diagnostic Criteria in a Hospital Setting in South Korea.Annals of dermatology · 2025Article
- Prevalence and Comorbidities of Atopic Dermatitis in Korean Children and Adolescents From 1995 to 2022: A Population-Based Study.Allergy, asthma & immunology research · 2025Article
- 2023 Consensus Korean Diagnostic Criteria for Atopic Dermatitis.Annals of dermatology · 2025Article
- Cutaneous Manifestations in Patients on Hemodialysis and Assessment of the Changes in Quality of Life After 12 Weeks of Treatment by a Dermatologist.Journal of Korean medical science · 2024Article
- Eczema in early childhood increases the risk of allergic multimorbidity.Clinical and translational allergy · 2024Article
- Type 2 Innate Lymphoid Cells and Skin Fibrosis in a Murine Model of Atopic Dermatitis-Like Skin Inflammation.Journal of Korean medical science · 2024Article
- Prevalence of Severe Atopic Dermatitis and Comorbid Chronic Systemic Diseases Is Increasing in Korean Children and Adolescents.Allergy, asthma & immunology research · 2024Article
- Moderate to severe atopic dermatitis in children: focus on systemic Th2 cytokine receptor antagonists and Janus kinase inhibitors.Clinical and experimental pediatrics · 2024Article
- Associations Between Phthalate, Eosinophil, and Aeroallergen Sensitization in Schoolchildren.Journal of Korean medical science · 2023Article
- Review
- Alterations of Epidermal Lipid Profiles and Skin Microbiome in Children With Atopic Dermatitis.Allergy, asthma & immunology research · 2023Article
- Association between household income levels and nutritional intake of allergic children under 6 years of age in Korea: 2019 Korea National Health and Nutrition Examination Survey and application of machine learning.Frontiers in public health · 2023Article
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Authors and funding
24 authors at 13 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtopic dermatitis (AD) is a heterogeneous disease with different age of onset, disease course, clinical symptoms, severity, and risk of comorbidity. The characteristics of children with AD also vary by age or country. However, little is known about the clinical characteristics of AD in Korean school-aged children and adolescents. Furthermore, there are few studies on phenotypic differences according to onset age. This study aimed to explore the clinical characteristics and phenotypes according to onset age and severity of AD in children and adolescents in Korea.
methodsAD patients aged 6-18 years who presented to 18 hospitals nationwide were surveyed. The patients were examined for disease severity by pediatric allergy specialists, and data on history of other allergic diseases, familial allergy history, onset age, trigger factors, lesion sites, treatment history and quality of life were collected. The results of the patient's allergy test were also analyzed. The patients were classified into infancy-onset (< 2 years of age), preschool-onset (2-5 years of age), and childhood-onset (≥ 6 years of age) groups. Study population was analyzed for clinical features according to onset-age groups and severity groups.
resultsA total of 258 patients with a mean age of 10.62 ± 3.18 years were included in the study. Infancy-onset group accounted for about 60% of all patients and presented significantly more other allergic diseases, such as allergic rhinitis and asthma (
conclusionThis study analyzed the clinical features of AD in Korean children and adolescents through a multicenter nationwide study and demonstrated the phenotypic differences according to onset age and severity. Considering the findings that the early-onset group is more severe and accompanied by more systemic allergic diseases, early management should be emphasized in young children and infants.
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