Evidence map›Paper›PMID 35075820›Full record

ArticleClinical and translational medicine2022

Antagonism of nicotinic acetycholinergic receptors by CN-105, an apoE-mimetic peptide reduces stroke-induced excitotoxicity.

Miaomiao Xue, Shuya Li, Mingzhi Xu, Li Yan, Daniel T Laskowitz, Brad J Kolls, Gang Chen, Xiaohong Qian, Yongjun Wang, Haifeng Song and 1 more

Open access · goldAbstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. ApoE Mimetic Peptides as Therapy for Traumatic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Miaomiao XueState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Shuya LiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Mingzhi XuState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Li YanICE Bioscience Inc., Beijing, China.
Daniel T LaskowitzDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Brad J KollsDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Gang ChenGuangdong Cerebtron Biotech Ltd., Guangdong, China.
Xiaohong QianState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Yongjun WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Haifeng SongState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.
Yi WangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.ORCID 0000-0002-4954-6317
Beijing Proteome Research Center · CNCapital Medical University · CNDuke University · USBioscience (China) · CN

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Beijing Municipal Administration of Hospitals Incubating Program PX2018022Ministry of Science and Technology (China) 2015ZX09501007-002-05Ministry of Science and Technology (China) 2015ZX09501008-006National Science Foundation of China 31400733National Science Foundation of China 81272701/H1617NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Inflammatory AgentsApolipoproteins EHumansNeurotoxinsPeptide FragmentsReceptors, NicotinicStrokeAnti-Inflammatory Agentsapolipoprotein E (133-149)Apolipoproteins ENeurotoxinsPeptide FragmentsReceptors, Nicotinic

Identifiers

PMID35075820
PMCPMC8787096
OpenAlexW4207048274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.