Evidence map›Paper›PMID 35075809›Full record

ArticlePhysiological reports2022

Anti-Müllerian hormone and vascular dysfunction in women with chronic kidney disease.

Sandra M Dumanski, Todd J Anderson, Kara A Nerenberg, Jayna Holroyd-Leduc, Jennifer MacRae, Satish R Raj, Amy Metcalfe, Sharanya Ramesh, Cindy Z Kalenga, Darlene Sola and 2 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sandra M DumanskiDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-1165-6200
Todd J AndersonDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Kara A NerenbergDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jayna Holroyd-LeducDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jennifer MacRaeDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Satish R RajLibin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Amy MetcalfeDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Sharanya RameshFaculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.
Cindy Z KalengaLibin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Darlene SolaLibin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Milada PajevicLibin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Sofia B AhmedDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-3000-2229
University of Calgary · CALibin Cardiovascular Institute of Alberta · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Young women with chronic kidney disease (CKD) have disproportionately increased risk of cardiovascular mortality. Reduced anti-Müllerian hormone (AMH) is linked to poor cardiovascular outcomes in the general population, but whether AMH is associated with increased cardiovascular risk in the high-risk CKD population is unknown. This study examined the association between AMH and vascular function, validated markers of cardiovascular risk, in women with CKD. An exploratory cross-sectional study was performed in 47 young women with CKD. Laboratory measurements of AMH were collected. Using standardized protocols, endothelial function was measured with brachial artery flow-mediated dilation and hyperemic velocity time integral. Arterial stiffness was measured with aortic augmentation index and pulse wave velocity. Multivariate linear regression analyses were utilized to evaluate the association between AMH levels and each measure of vascular health. Forty women (36 ± 7 years) with non-dialysis-dependent CKD and 7 women (38 ± 6 years) with dialysis-dependent CKD participated. AMH levels were inversely associated with age (p = 0.01) but not associated with eGFR (p = 0.59) or dialysis status (p = 0.97). AMH was associated with brachial artery flow-mediated dilation (R

Indexed as

Renal Insufficiency, ChronicVascular StiffnessAnti-Mullerian HormoneBrachial ArteryCross-Sectional StudiesFemaleHumansPulse Wave AnalysisAnti-Mullerian Hormonearterial stiffnesscardiovascularendothelial dysfunctionfertilityovarian function

Identifiers

PMID35075809
PMCPMC8787421
OpenAlexW4210345399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.