SynthesisJournal of clinical nursing2022
Effect of a game-based intervention on preoperative pain and anxiety in children: A systematic review and meta-analysis.
Synthesis in Journal of clinical nursing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 8 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Virtual reality for reducing pain, anxiety, and distress in children, adolescents, and young adults with cancer: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2026Pooled it
- Preoperative Virtual Reality for Pediatric Patients Undergoing General Anesthesia: A Meta-Analysis of Randomized Controlled Trial.Paediatric anaesthesia · 2025Pooled it
- Effects of virtual reality on pain, anxiety, and delirium in pediatric surgery: a systematic review and meta-analysis.Pediatric surgery international · 2025Pooled it
- Effects of Virtual Reality-Based Interventions on Preoperative Anxiety in Patients Undergoing Elective Surgery With Anesthesia: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- The use of games in the classroom to promote mental health knowledge and healthy attitudes in adolescents: a systematic review.Frontiers in psychiatry · 2025Pooled it
- Effect of a game-based intervention on preoperative pain and anxiety in children: A systematic review and meta-analysis.Journal of clinical nursing · 2022Pooled it
- Effect of video-based interventions on emergence delirium in pediatric patients: a systematic review and meta-analysis of randomized controlled trials.Jornal de pediatriaPooled it
- Effect of recorded mother's voice on emergence delirium in pediatric patients: a systematic review with meta-analysis.Jornal de pediatriaPooled it
- Role of virtual reality exposure before elective day care surgery to reduce patient's distress.Updates in surgery · 2026Trial
- The effect of electric ride-on cars use during transport to the operating room on preoperative anxiety in children: a cluster randomized controlled trial.Pediatric surgery international · 2026Trial
- The effect of stress ball use during caesarean delivery on maternal anxiety, postoperative pain, and breastfeeding success: a prospective, randomized trial.Revista da Associacao Medica Brasileira (1992) · 2026Trial
- Play dough or balloon blowing? A clinical trial comparing creative interventions for reducing preoperative anxiety in children aged 4-8 years.BMC pediatrics · 2025Trial
- The preparation of children for day surgery from the parent's viewpoint: A mixed methods study.Nursing open · 2024Trial
- Assessing Pain in Children: A Narrative Review of Distraction-Based Interventions and Outcome Measurement Tools.Paediatric & neonatal pain · 2026Review
- Effectiveness of a card game-based intervention in alleviating preoperative anxiety in children: a randomized controlled trial.World journal of pediatrics : WJP · 2026Article
- Preoperative Oral Tasipimidine in Dogs Undergoing Elective Ovariectomy: Anxiolysis, Handling Quality and Cardiovascular Effects.Veterinary sciences · 2026Article
- Higher Education as a Driver for the Humanization of Pediatric Pain Care (HUPEDCARE): Protocol of a Multicenter Study.European journal of investigation in health, psychology and education · 2026Article
- Preoperative interventions for reducing anxiety in school-age children undergoing surgery: a network meta-analysis.The Cochrane database of systematic reviews · 2026Article
- Implementation of Virtual Reality for Postoperative Recovery in an Adolescent Idiopathic Scoliosis Population: A Prospective Pilot Study.Pediatric neurosurgery · 2026Article
- Effectiveness of Thumb Sleeve Distraction and Pop-It Therapeutic Play in Reducing Dental Anxiety and Pain in Children Aged 4-6 Years Undergoing Mandibular Alveolar Nerve Block: A Randomized Controlled Trial.International journal of dentistry · 2026Article
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGames are increasingly being used as a means of alleviating pain and anxiety in paediatric patients, in the view that this form of distraction is effective, non-invasive and non-pharmacological.
aimsTo determine whether a game-based intervention (via gamification or virtual reality) during the induction of anaesthesia reduces preoperative pain and anxiety in paediatric patients.
methodsA systematic review with meta-analysis of randomised controlled trials was performed in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and using RevMan software. The review was based on a search of the EMBASE, CINAHL, Medline, SciELO and Scopus databases, conducted in July 2021. No restriction was placed on the year of publication.
results26 studies were found, with a total study population of 2525 children. Regarding pain reduction, no significant differences were reported. For anxiety during anaesthesia induction, however, a mean difference of -10.62 (95% CI -13.85, -7.39) on the Modified Yale Preoperative Anxiety Scale, in favour of game-based intervention, was recorded.
conclusionsGame-based interventions alleviate preoperative anxiety during the induction of anaesthesia in children. This innovative and pleasurable approach can be helpful in the care of paediatric surgical patients. RELEVANCE TO CLINICAL PRACTICE: In children, preoperative management is a challenging task for healthcare professionals, and game-based strategies could enhance results, improving patients' emotional health and boosting post-surgery recovery. Distractive games-based procedures should be considered for incorporation in the pre-surgery clinical workflow in order to optimise healthcare.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.