Evidence map›Paper›PMID 35075631›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2022

Clinical characteristics and surgical management of endometriosis-associated infertility: A multicenter prospective cohort study.

Aishwarya V Bhurke, Pramathes DasMahapatra, Sheila Balakrishnan, Shagufta A Khan, Sally Mortlock, Vinita Das, Nirmala Chellamma, Sowmini Cheruvara Vadakkathil, Aarti Srivastava, Amiya Majumdar and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. The interplay between endometriosis and obesity.Trends in endocrinology and metabolism: TEM · 2025
    Review
  4. Review
  5. Article
  6. Endometriosis and inflammatory immune responses: Indian experience.American journal of reproductive immunology (New York, N.Y. : 1989) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Aishwarya V BhurkeClinical Research Laboratory, Indian Council of Medical Research-National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.ORCID https://orcid.org/0000-0002-2000-2076
Pramathes DasMahapatraSpectrum Clinic & Endoscopy Research Institute, Kolkata, India.
Sheila BalakrishnanDepartment of Reproductive Medicine, Government Medical College, Thiruvananthapuram, India.
Shagufta A KhanClinical Research Laboratory, Indian Council of Medical Research-National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.
Sally MortlockInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0003-2327-9465
Vinita DasDepartment of Obstetrics and Gynecology, King George's Medical University (KGMU), Lucknow, India.
Nirmala ChellammaDepartment of Obstetrics and Gynecology, Sree Avittam Thirunal Hospital, Government Medical College, Thiruvananthapuram, India.
Sowmini Cheruvara VadakkathilDepartment of Obstetrics and Gynecology, Sree Avittam Thirunal Hospital, Government Medical College, Thiruvananthapuram, India.
Aarti SrivastavaDepartment of Obstetrics and Gynecology, King George's Medical University (KGMU), Lucknow, India.
Amiya MajumdarSpectrum Clinic & Endoscopy Research Institute, Kolkata, India.
Achhelal PasiAirport Health Organization, Sahar, Mumbai, India.
Geetanjali SachdevaDepartment of Cell Physiology and Pathology, ICMR-NIRRCH, Mumbai, India.
Grant W MontgomeryInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-4140-8139
Rahul K GajbhiyeClinical Research Laboratory, Indian Council of Medical Research-National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.ORCID https://orcid.org/0000-0003-3864-1818
National Institute for Research in Reproductive Health · INGovernment Medical College and Hospital · INKing George's Medical University · INSpectrum Clinical Research (India) · INThe University of Queensland · AUAirbus (India) · INGovernment Medical College · IN

Funding

DBT-Wellcome Trust India Alliance IA/CPHI/18/1/503933Wellcome Trust
6 · The paper itself

Abstract

objectiveTo study clinical, surgical characteristics and the relationship between endometriosis lesion types and conception rate after surgery in infertile women with endometriosis.

methodsA prospective, multicenter cohort of 204 women (age 20-35 years) with endometriosis was followed up post-surgery between November 2017 and February 2020 at three tertiary-care hospitals.

resultsBased on the severity of endometriosis lesion type, deep infiltrating endometriosis (DIE) (81/204, 39.7%) was the most common lesion; followed by ovarian endometriosis (OMA) (64/204, 31.4%), and superficial peritoneal endometriosis (SUP) (59/204, 28.9%). Endometriosis patients had a single lesion type (94/204, 46.1%), two lesion types (77/204, 37.7%), or three lesion types (33/204, 16.2%) with significant differences between regions (P < 0.001). Around 40% (37/95) of obese women had SUP (P = 0.003) whereas 78% (14/18) of underweight women had DIE (P < 0.001). Significant differences in mean Endometriosis Fertility Index scores between endometriosis lesion types and patients with one, two, and three types of lesions were observed (P < 0.001). The majority (22/32, 68.8%) of the women conceived naturally after the surgery. Half (16/32; 50%) of the women with a single lesion type conceived after the surgery; of which most (13/16, 81.2%) had SUP, followed by OMA (2/16, 12.5%), and DIE (1/16, 6.3%).

conclusionWomen with SUP and only one type of endometriotic lesion were more likely to conceive post-surgery.

Indexed as

EndometriosisInfertility, FemaleAdultFemaleFertilityHumansPeritoneumProspective StudiesYoung Adultanatomical distributiondeep infiltrating endometriosisendometriomainfertilitymanagementsuperficial peritoneal endometriosis

Identifiers

PMID35075631
PMCPMC7615031
OpenAlexW4207016964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.