Evidence map›Paper›PMID 35075493›Full record

ArticleBulletin of environmental contamination and toxicology2022

Gonadal Atresia, Estrogen-Responsive, and Apoptosis-Specific mRNA Expression in Marine Mussels from the East China Coast: A Preliminary Study.

Jingmin Zhu, Jiana Li, Emma C Chapman, Huahong Shi, Corina M Ciocan, Kai Chen, Xiaodong Shi, JunLiang Zhou, Peiying Sun, Yueyao Zheng and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bulletin of environmental contamination and toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jingmin ZhuState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Jiana LiState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Emma C ChapmanDepartment of Biological and Marine Sciences, Hardy Building, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
Huahong ShiState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Corina M CiocanSchool of Pharmacy and Biomolecular Sciences, University of Brighton, Lewes Road, Brighton, BN2 4GJ, UK.
Kai ChenState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Xiaodong ShiState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
JunLiang ZhouState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Peiying SunState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Yueyao ZhengState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China.
Jeanette M RotchellState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China. J.Rotchell@hull.ac.uk.ORCID http://orcid.org/0000-0002-7371-6080
East China Normal University · CNUniversity of Hull · GBUniversity of Brighton · GB

Funding

National Natural Science Foundation of China 41171376National Natural Science Foundation of China 41571467State Key Laboratory of Estuarine and Coastal Research SKLEC-KF201405
6 · The paper itself

Abstract

This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36 ng/L, < LOD-3.88 ng/g wet weight of tissue for BPA) relative to worldwide freshwater environments, but high oocyte follicle atresia incidences (up to 26.6%) occurred at selected sites. Expression of estrogen-responsive ER2 was significantly increased in males relative to females at sites with high atresia incidences in females. A second estrogen-responsive gene, V9, was significantly increased at two sites in April in females relative to males; the opposite was true for the remaining two sites. Apoptosis-specific genes (Bcl-2, fas) showed elevated expression in males relative to females at the site with the highest atresia incidence. These results provide coastal estrogen levels and the utility of several estrogen-specific molecular-level markers for marine mussels.

Indexed as

BivalviaMytilusAnimalsApoptosisEstrogensFemaleGonadsMaleRNA, MessengerEstrogensRNA, MessengerApoptosisAtresiaEstrogenMytilus

Identifiers

PMID35075493
PMCPMC9188513
OpenAlexW4207047184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.