Evidence map›Paper›PMID 35075457›Full record

ArticlebioRxiv : the preprint server for biology2022

Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection.

Qian Li, Kadambari Vijaykumar, Scott E Philips, Shah S Hussain, Van N Huynh, Courtney M Fernandez-Petty, Jacelyn E Peabody Lever, Jeremy B Foote, Janna Ren, Javier Campos-Gómez and 16 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 2 institutions in 1 country.

Qian LiDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Kadambari VijaykumarDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Scott E PhilipsDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Shah S HussainDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Van N HuynhDepartment of Graduate Biomedical Sciences Program, University of Alabama at Birmingham, Birmingham, AL, United States.
Courtney M Fernandez-PettyDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Jacelyn E Peabody LeverDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Jeremy B FooteDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Janna RenDepartment of Chemistry, University of Alabama at Birmingham, Birmingham, AL, United States.
Javier Campos-GómezDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Farah Abou DayaDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Nathaniel W HubbsDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Harrison KimDepartment of Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Ezinwanne OnuohaDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, United States.
Evan R BoitetDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Lianwu FuDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Hui Min LeungWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Linhui YuWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Thomas W DetchemendyDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Levi T SchaefersDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Jennifer L TipperDepartments of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Lloyd J EdwardsDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
Sixto M LealDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Kevin S HarrodDepartments of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Guillermo J TearneyWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Steven M RoweDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
University of Alabama at Birmingham · USHarvard University · US

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008361 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YACOUBIAN, TALENE ALENE · 1992 to 2024
$16.8M
Translational Program in CFTR-Related Airway DiseasesR35HL135816 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROWE, STEVEN MARK · 2017 to 2022
$6.3M
Training Program in Lung Biology and Translational MedicineT32HL105346 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GAGGAR, AMIT · 2010 to 2025
$5.0M
Influenza regulation of epithelial pneumococcal host defense.R01HL149944 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HARROD, KEVIN S · 2020 to 2023
$1.5M
Mucus Matters: Mucociliary Physiology in Pulmonary FibrosisF31HL146083 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVER, JACELYN EMILY PEABODY · 2019 to 2020
$77k
NHLBI NIH HHS F31 HL146083NHLBI NIH HHS R01 HL149944NHLBI NIH HHS R35 HL135816NHLBI NIH HHS T32 HL105346NIDDK NIH HHS P30 DK072482NIGMS NIH HHS T32 GM008361
6 · The paper itself

Abstract

Substantial clinical evidence supports the notion that ciliary function in the airways plays an important role in COVID-19 pathogenesis. Although ciliary damage has been observed in both

Identifiers

PMID35075457
PMCPMC8786228
OpenAlexW4210792190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.