Evidence map›Paper›PMID 35075385›Full record

Trial reportJournal of healthcare engineering2022

Effect of Huaiqihuang Granules Combined with Comprehensive Nursing on Children with Primary Nephrotic Syndrome.

Guiyun Yang, Huanqin Yang, Shifang Cui, Jinling Shan

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Corticosteroid therapy for nephrotic syndrome in children.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guiyun YangChild Health Care Department, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.
Huanqin YangChild Health Care Department, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.
Shifang CuiDepartment of Paediatrics, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.
Jinling ShanChild Health Care Department, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.ORCID 0000-0003-0521-609X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo observe the effect of Huaiqihuang granules combined with comprehensive nursing intervention on children with primary nephrotic syndrome (PNS) and its effect on renal function index.

methodsA total of 104 patients were included, and the patients were randomly divided into two groups, with 52 cases in each group. The control group was treated with glucocorticoid, and the study group was treated with Huaiqihuang granules. The clinical efficacy of the two groups was observed. The levels of TG, TC, EGFR, 24 h UTP, BUN, Scr, IgA, IgG, IgM, IFN-

resultsThe effective rate of the study group (94.23%) was significantly higher than that of the control group (78.85%). Before treatment, there was no significant difference in TG and TC levels between the two groups. After treatment, the levels of TG and TC in both groups were decreased, and the decrease was more obvious in the study group. Compared with before treatment, the levels of 24 h UTP, BUN, Scr, IFN-

conclusionsHuaiqihuang granules combined with comprehensive nursing treatment in children with PNS can reduce the occurrence of recent recurrence and adverse reactions and improve the cellular immune function and renal function.

Indexed as

Nephrotic SyndromeChildDrugs, Chinese HerbalErbB ReceptorsFemaleHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MMaleTumor Necrosis Factor-alphaUridine TriphosphateDrugs, Chinese HerbalErbB Receptorshuai qi huangImmunoglobulin AImmunoglobulin GImmunoglobulin MTumor Necrosis Factor-alphaUridine Triphosphate

Identifiers

PMID35075385
PMCPMC8783717
OpenAlexW4206267569

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.