Evidence map›Paper›PMID 35075349›Full record

ArticleMediators of inflammation2022

Roles Played by the PI3K/Akt/HIF-1

Ke-Jia Cheng, Min-Li Zhou, Yong-Cai Liu, Shui-Hong Zhou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Autophagy in chronic rhinosinusitis with or without nasal polyps.Frontiers in cell and developmental biology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ke-Jia ChengDepartment of Otolaryngology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-5078-1448
Min-Li ZhouDepartment of Otolaryngology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-9254-1389
Yong-Cai LiuDepartment of Otolaryngology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0003-3680-3975
Shui-Hong ZhouDepartment of Otolaryngology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0002-7163-2289
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Chinese subtype of CRSwNP may have a unique pathogenesis. This study was designed to seek the role of the PI3K/Akt/HIF-1

methodsThe total IgE, ECP, and IL-17A levels were determined by UniCAP100 and ELISA. The activity of MPO was detected by the biochemical techniques. The protein expressions of HIF-1

resultsThe CRSwNP group showed significantly elevated MPO activity, PI3K, p-AKT protein, HIF-1

conclusionThe PI3K/Akt/HIF-1

Indexed as

Nasal PolypsRhinitisSinusitisChinaChronic DiseaseHumansHypoxia-Inducible Factor 1, alpha SubunitInterleukin-17Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktHypoxia-Inducible Factor 1, alpha SubunitIL17A protein, humanInterleukin-17Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

Identifiers

PMID35075349
PMCPMC8783707
OpenAlexW4206032049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.