Evidence map›Paper›PMID 35075123›Full record

ArticleNature communications2022

Hyperpolarised

Nikita Sushentsev, Mary A McLean, Anne Y Warren, Arnold J V Benjamin, Cara Brodie, Amy Frary, Andrew B Gill, Julia Jones, Joshua D Kaggie, Benjamin W Lamb and 12 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Review
  3. Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026
    Review
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  6. Ultra-low fieldCommunications chemistry · 2026
    Article
  7. Review
  8. Preclinical Applications of Magnetic Resonance Imaging in Oncology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  9. Review
  10. Scalable Hyperpolarized MRI Enabled by Ace-SABRE of [1-Angewandte Chemie (International ed. in English) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Lactate and lactylation in cancer.Signal transduction and targeted therapy · 2025
    Review
  15. Article
  16. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  17. Review
  18. Theranostics · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 4 countries.

Nikita SushentsevDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-4500-9714
Mary A McLeanDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Anne Y WarrenDepartment of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Arnold J V BenjaminDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2063-8258
Cara BrodieCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Amy FraryDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4373-3517
Andrew B GillDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Julia JonesCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9819-8091
Joshua D KaggieDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-6706-3442
Benjamin W LambDepartment of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID http://orcid.org/0000-0003-2220-893X
Matthew J LockeDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Jodi L MillerCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-6870-204X
Ian G MillsPatrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Andrew N PriestDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-9771-4290
Fraser J L RobbGE Healthcare, Aurora, OH, USA.
Nimish ShahDepartment of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Rolf F SchulteGE Healthcare, Munich, Germany.
Martin J GravesDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-4327-3052
Vincent J GnanapragasamDepartment of Urology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Kevin M BrindleCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-3883-6287
Tristan Barrett *Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK. tb507@medschl.cam.ac.uk.
Ferdia A Gallagher *Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-4784-5230
University of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GBAurora Health Care · USQueen's University Belfast · GBSiemens Healthineers (Germany) · DE

Funding

Cancer Research UK 16628Cancer Research UK 17242Cancer Research UK 27150Cancer Research UK 28667Cancer Research UK C19212/A16628Cancer Research UK C19212/A27150Cancer Research UK C197/A17242Cancer Research UK C197/A29580Wellcome Trust
6 · The paper itself

Abstract

Hyperpolarised magnetic resonance imaging (HP

Indexed as

AgedAged, 80 and overCohort StudiesEpithelial CellsGlycolysisHumansL-Lactate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedMonocarboxylic Acid TransportersMuscle ProteinsProspective StudiesProstatic NeoplasmsPyruvic AcidStromal CellsL-Lactate DehydrogenaseMonocarboxylic Acid TransportersMuscle ProteinsPyruvic AcidSLC16A4 protein, human

Identifiers

PMID35075123
PMCPMC8786834
OpenAlexW4207038339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.