Evidence map›Paper›PMID 35074845›Full record

Observational studyClinical journal of the American Society of Nephrology : CJASN2022

Health-Related Quality-of-Life Trajectories over Time in Older Men and Women with Advanced Chronic Kidney Disease.

Nicholas C Chesnaye, Yvette Meuleman, Esther N M de Rooij, Ellen K Hoogeveen, Friedo W Dekker, Marie Evans, Agneta A Pagels, Fergus J Caskey, Claudia Torino, Gaetana Porto and 5 more

Open access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Clinical journal of the American Society of Nephrology : CJASN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Trial
  3. The evolution of symptom burden in older men and women with advanced CKD.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neuropathic Pain, Polyneuropathy, and Quality of Life in Patients Receiving Dialysis.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Observational
  9. Article
  10. Review
  11. Article
  12. Review
  13. Heart Failure-Type Symptom Score Trajectories in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 6 countries.

Nicholas C ChesnayeEuropean Renal Association-European Dialysis and Transplant Association Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands n.c.chesnaye@amsterdamumc.nl.ORCID 0000-0003-4883-9174
Yvette MeulemanDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-9891-2109
Esther N M de RooijDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-3017-2885
Ellen K HoogeveenDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-5482-2013
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Marie EvansRenal Unit, Department of Clinical Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Agneta A PagelsDepartment of Medicine, Karolinska Institute, Stockholm, Sweden.
Fergus J CaskeyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Claudia TorinoInstitute of Clinical Physiology-National Research Council, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy.
Gaetana PortoGrande Ospedale Metropolitano, Bianchi Melacrino Morelli, Reggio Calabria, Italy.
Maciej SzymczakDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.ORCID 0000-0002-1248-081X
Christiane DrechslerDivision of Nephrology, University Hospital of Wurzburg, Wurzburg, Germany.
Christoph WannerDivision of Nephrology, University Hospital of Wurzburg, Wurzburg, Germany.ORCID 0000-0001-9507-5301
Kitty J JagerEuropean Renal Association-European Dialysis and Transplant Association Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
EQUAL Study Investigators
Leiden University Medical Center · NLAmsterdam UMC Location University of Amsterdam · NLKarolinska University Hospital · SEUniversitätsklinikum Würzburg · DEAzienda ospedaliera "Bianchi-Melacrino-Morelli" · ITNational Research Council · ITUniversity of Bristol · GBWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe effect of sex on longitudinal health-related quality of life remains unknown in CKD. Here we assess differences in the sex-specific evolution of health-related quality of life in older men and women with advanced CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The European Quality Study on Treatment in Advanced Chronic Kidney Disease is a European observational prospective cohort study in referred patients with CKD and an incident eGFR<20 ml/min per 1.73 m

resultsWe included 5345 health-related quality-of-life measurements in 1421 participants. At baseline, women had considerably lower mean Physical Component Summary (42) and Mental Component Summary (60) compared with men (Physical Component Summary: 55; Mental Component Summary: 69;

conclusionsAmong older men and women with advanced CKD, women had lower health-related quality of life at baseline, but men experienced a more rapid decline in health-related quality of life over time.

Indexed as

Quality of LifeRenal Insufficiency, ChronicAgedAged, 80 and overAge FactorsCohort StudiesFemaleHumansMaleProspective StudiesSeverity of Illness IndexTime Factorsagedchronic kidney diseasequality of lifesex differences

Identifiers

PMID35074845
PMCPMC8823930
OpenAlexW4206908298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.