Evidence map›Paper›PMID 35074696›Full record

ArticleDrug and alcohol dependence2022

Medications for opioid use disorder during pregnancy: Access and continuity in a state women's prison facility, 2016-2019.

Andrea K Knittel, Rita A Swartzwelder, Samantha Zarnick, Tamy Harumy Moraes Tsujimoto, Timelie Horne, Feng-Chang Lin, James Edwards, Elton Amos, James Alexander, John Thorp and 1 more

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Bringing MOUD "In House": Implementing an Internal MOUD Program During Pregnancy in a State Prison.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2026
    Article
  2. Article
  3. Justice Core: An Innovative Response to Incarceration During Pregnancy in North Carolina.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2025
    Article
  4. Carceral Health Care.The New England journal of medicine · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Andrea K KnittelDivision of General Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. Electronic address: aknittel@umich.edu.
Rita A SwartzwelderUniversity of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Samantha ZarnickUniversity of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Tamy Harumy Moraes TsujimotoDepartment of Biostatistics, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Timelie HorneUniversity of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Feng-Chang LinDepartment of Biostatistics, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
James EdwardsWakeMed Maternal-Fetal Medicine, Raleigh, NC, USA.
Elton AmosNorth Carolina Department of Public Safety, Raleigh, NC, USA.
James AlexanderNorth Carolina Department of Public Safety, Raleigh, NC, USA.
John ThorpDivision of General Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Hendree E JonesUNC Horizons, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USNorth Carolina Department of Public Safety · USWakeMed · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Advancing womens reproductive health through research: the UNC WRHR Career Development ProgramK12HD103085 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Benjamin H. Chi, Genevieve S. Neal-Perry · 2020 to 2026
$2.1M
NCATS NIH HHS UL1 TR002489NICHD NIH HHS K12 HD103085
6 · The paper itself

Abstract

backgroundAlthough medications to treat opioid use disorder (MOUD) are the standard of care during pregnancy, there are many potential gaps in the cascade of care for pregnant people experiencing incarceration.

methodsWe conducted a retrospective cohort study of pregnant people with opioid use disorder incarcerated in a Southeastern women's prison from 2016 to 2019. The primary outcomes were access to MOUD during incarceration and continuity in the community. We used descriptive statistics to summarize aspects of our sample and logistic regression to identify predictors of MOUD receipt during incarceration.

resultsOf the 279 pregnant people with OUD included in the analysis, only 40.1% (n = 112) received MOUD during incarceration, including 67 (59.8%) who received methadone and 45 (40.1%) who received buprenorphine. Less than one-third of the participants were referred to a community MOUD provider (n = 83, 30%) on return to the community. Significant predictors of MOUD receipt included medium/close custody level during incarceration, incarceration during the latter portion of the study period, pre-incarceration heroin use, and receipt of pre-incarceration MOUD.

conclusionsAlthough prisons can serve as an important site of retention in MOUD for some pregnant people, there were substantial gaps in initiation of MOUD and retention in MOUD among pregnant people with OUD imprisoned in the Southeast during the study period.

Indexed as

BuprenorphineOpioid-Related DisordersFemaleHumansOpiate Substitution TreatmentPregnancyPrisonsRetrospective StudiesBuprenorphine

Identifiers

PMID35074696
PMCPMC8946772
OpenAlexW4205426117

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.