Mechanism for R-loop formation remote from the transcription start site: Topological issues and possible facilitation by dissociation of RNA polymerase.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed.

1. Polymerase face-off: emerging concepts in transcription-replication coordination.EMBO reports · 2026
   Review
2. DNA lesions can frequently precede DNA:RNA hybrid accumulation.Nature communications · 2025
   Article
3. Localization of Potential Energy in Hydrogen Bonds of theInternational journal of molecular sciences · 2025
   Article
4. Topology and kinetics of R-loop formation.Biophysical journal · 2022
   Article
5. Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5.Cell reports · 2022
   Article

Corrections and comments

• Comment on
  Defining R-loop classes and their contributions to genome instability.2021

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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