Evidence map›Paper›PMID 35074517›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Mortality by COVID-19 Before Vaccination - One Year Experience of Hospitalized Patients in Madrid.

Víctor Moreno-Torres, Alejandro Muñoz-Serrano, Jorge Calderón-Parra, Patricia Mills-Sánchez, Ilduara Pintos-Pascual, Celia Rodríguez-Olleros, Fátima Ibánez-Estéllez, Yale Tung-Chen, Antonio Ramos-Martínez, Juan A Vargas-Núñez and 2 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. COVID-19 outcome trends by vaccination status in Canada, December 2020-January 2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  2. Review
  3. Review
  4. Article
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  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Víctor Moreno-TorresInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: victor.moreno.torres.1988@gmail.com.
Alejandro Muñoz-SerranoInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: alexmuser@gmail.com.
Jorge Calderón-ParraInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: Jorge050390@gmail.com.
Patricia Mills-SánchezInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: pamillssa@gmail.com.
Ilduara Pintos-PascualInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: Ilduarapintos@gmail.com.
Celia Rodríguez-OllerosInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: celia.rodriguezolleros@gmail.com.
Fátima Ibánez-EstéllezInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: fatima_ibaest@hotmail.com.
Yale Tung-ChenInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain. Electronic address: yale.tung.chen@gmail.com.
Antonio Ramos-MartínezInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Medicine Department, School of Medicine. Universidad Autónoma de Madrid, Madrid, Spain. Electronic address: aramos220@gmail.com.
Juan A Vargas-NúñezInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Medicine Department, School of Medicine. Universidad Autónoma de Madrid, Madrid, Spain. Electronic address: juanantonio.vargas@salud.madrid.org.
Prof Valentín Cuervas-MonsInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Medicine Department, School of Medicine. Universidad Autónoma de Madrid, Madrid, Spain. Electronic address: valentin.cuervasmons@salud.madrid.org.
Carmen de MendozaInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; CEU-San Pablo, University, Madrid, Spain. Electronic address: cmendoza.cdm@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to analyze the mortality and characteristics of deceased patients with COVID-19 during the first year of the pandemic.

methodsAll admissions owing to COVID-19 at a tertiary hospital in Madrid were analyzed. Three waves were considered: March 2020 to June 2020, July 2020 to November 2020, and December 2020 to April 2021.

resultsA total of 3,676 patients were identified. Among inpatients, no differences regarding age, sex, length of admission, or mortality were found between the 3 waves (p >0.05). The overall mortality rate was 12.9%. Among deceased patients, the median age was 82 years and the median Charlson Comorbidity Index was 6. Considering the main predictors for mortality by COVID-19 (age, sex, and concomitant comorbidities), only patients with previous lung disease were more prevalent in the third period (p <0.01). Finally, higher intensive care unit admission rates, a lower rate of patients coming from nursing homes, and a lower rate of patients with dementia were noted in the third period (p <0.05) among deceased patients.

conclusionOne year after the onset of the pandemic, the mortality rate of hospitalized patients and the profile of non-survivors have not changed significantly. In the absence of vaccine benefits, advanced age and multiple pathologies are uniform characteristics of non-survivors.

Indexed as

COVID-19Aged, 80 and overComorbidityHospital MortalityHumansPandemicsRetrospective StudiesSARS-CoV-2VaccinationcomorbiditiesCOVID-19mortality rateSpain

Identifiers

PMID35074517
PMCPMC8782738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.