SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022
Craniofacial features in children with obstructive sleep apnea: a systematic review and meta-analysis.
Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Upper airway dimensions in pediatric obstructive sleep-disordered breathing: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- The effect of rapid maxillary expansion on children with obstructive sleep apnea: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Do patients with different craniofacial patterns have differences in upper airway volume? A systematic review with network meta-analysis.European journal of orthodontics · 2024Pooled it
- The role of the hyoid bone in mandibular advancement: insights from functional appliance therapy in patients with skeletal class II - a prospective cohort study.Head & face medicine · 2025Trial
- Prevalence of sleep-disordered breathing in children and adolescents with large horizontal maxillary overjet due to mandibular retrognathia: a case-control study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Trial
- Craniofacial Features in Children with Sleep-Disordered Breathing: A Comparative Study.Journal of dentistry (Shiraz, Iran) · 2026Article
- Screening for Sleep-Disordered Breathing Risk in Pediatric Dental Care: A Protocol Combining Questionnaire-Based Stratification and Wearable Home Sleep Monitoring.Methods and protocols · 2026Article
- Biomechanical and Aerodynamic Modulation for Sinonasal Homeostasis in Craniofacial Orthopedics: A Comprehensive Review of RAMPA Therapy.Biomimetics (Basel, Switzerland) · 2026Review
- Paediatric Sleep-Disordered Breathing: Pharyngeal Airway and Lymphoid Tissues in Risk Assessment.Journal of clinical medicine · 2026Article
- Facial Patterns and Obstructive Sleep Apnea in Children Seeking for Orthodontic Treatment: Data From 3671 Polysomnographic Recordings.Orthodontics & craniofacial research · 2026Article
- Global trends in pediatric craniofacial growth and airway physiology research: insights from a five-year bibliometric analysis.Sleep & breathing = Schlaf & Atmung · 2026Review
- Maxillary Arch Expansion and Adenotonsillectomy in Prepubertal Children Diagnosed with Paediatric Obstructive Sleep Apnoea: An Interventional Study.Journal of clinical medicine · 2026Article
- Craniofacial Analysis of Lateral Cephalograms in Obstructive Sleep Apnea-An Exploratory Case-Control Study.Diagnostics (Basel, Switzerland) · 2026Article
- Clinical significance of mouth breathing as a marker of severity in pediatric obstructive sleep apnea.BMC oral health · 2026Article
- Risk of pediatric obstructive sleep apnea in preadolescent children with orthodontic anomalies: a diagnostic study.Frontiers in oral health · 2026Article
- Advances in research on dental occlusion and brain function: neuroimaging correlates and molecular mechanisms.Frontiers in neurology · 2026Review
- Utility of Cephalometry and Acoustic Pharyngometry for the Assessment of Moderate to Severe Obstructive Sleep Apnea Before Treatment in Childhood.Nature and science of sleep · 2026Article
- Noninvasive prescreening of pediatric adenoid hypertrophy using quantified MFCC statistics and clinical features: development and external validation.Frontiers in bioengineering and biotechnology · 2026Article
- Integrative Assessment of Cephalometric and Polysomnographic Features in Paediatric Obstructive Sleep Apnea: A Cross-Sectional Study.Nature and science of sleep · 2026Article
- Mandibular advancement devices in obstructive sleep apnea: diagnostic predictors for treatment response and clinical implications : A retrospective pilot cohort study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThis review aimed to evaluate the association between craniofacial features in children and adolescents with pediatric obstructive sleep apnea (OSA).
methodsSeven databases were searched to fulfill our research objectives. Clinical studies that included participants younger than 18 years with fully diagnosed OSA or without OSA and that evaluated skeletal, soft craniofacial features, or dental arch morphology were considered for this review. The risk of bias and certainty of evidence were assessed. A meta-analysis was performed when low methodological and clinical heterogeneity were detected. This review followed the protocols recommended by the Preferred Reporting Items for a Systematic Review and Meta-analysis (PRISMA-2020) guidelines.
resultsNine studies were identified at the end of the selection process, from which 5 did not report differences. Four studies reported differences between craniofacial features when OSA was compared to an asymptomatic control group. Mandibular retrognathia, reduced anteroposterior linear dimensions of the bony nasopharynx (decreased pharyngeal diameters at the levels of the adenoids), longer facial profile, and a narrower intercanine width were described among children with OSA. A meta-analysis was performed considering the studies with a similar methodological approach, and no differences were observed in all the considered cephalometric angles (SNA, SNB, ANB, NSBa, U1-L1, U1-SN). All the included studies were considered at low risk of bias even though some limitations were noted.
conclusionsDue to the very low to moderate level of certainty, neither an association nor a lack thereof between craniofacial morphology and pediatric OSA can be supported by these data. CITATION: Fagundes NCF, Gianoni-Capenakas S, Heo G, Flores-Mir C. Craniofacial features in children with obstructive sleep apnea: a systematic review and meta-analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.