Evidence map›Paper›PMID 35074035›Full record

ArticlePsychological medicine2023

The dynamic interplay between sleep and mood: an intensive longitudinal study of individuals with bipolar disorder.

K J S Lewis, K Tilling, K Gordon-Smith, K E A Saunders, A Di Florio, L Jones, I Jones, M C O'Donovan, J Heron

Open access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

K J S LewisDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0002-2220-6873
K TillingMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-1010-8926
K Gordon-SmithPsychological Medicine, University of Worcester, Worcester, UK.ORCID https://orcid.org/0000-0003-4083-1143
K E A SaundersDepartment of Psychiatry, Oxford University, Warneford Hospital, Oxford, OX3 7JX, UK.ORCID https://orcid.org/0000-0003-3448-9927
A Di FlorioDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0003-0338-2748
L JonesPsychological Medicine, University of Worcester, Worcester, UK.ORCID https://orcid.org/0000-0002-5122-8334
I JonesDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0001-5821-5889
M C O'DonovanDivision of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0001-7073-2379
J HeronMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-6199-5644
Cardiff University · GBUniversity of Bristol · GBUniversity of Worcester · GBOxford Health NHS Foundation Trust · GB

Funding

Medical Research Council MR/N027485/1Wellcome TrustWellcome Trust 220488/Z/20/Z
6 · The paper itself

Abstract

backgroundSleep disturbances are important symptoms to monitor in people with bipolar disorder (BD) but the precise longitudinal relationships between sleep and mood remain unclear. We aimed to examine associations between stable and dynamic aspects of sleep and mood in people with BD, and assess individual differences in the strength of these associations.

methodsParticipants (

resultsIncreased variability in insomnia symptoms was associated with increased mood variability. In the sample as a whole, we found strong evidence of bidirectional relationships between insomnia and depressive symptoms but only weak support for bidirectional relationships between insomnia and (hypo)manic symptoms. We found substantial variability between participants in the strength of prospective associations between insomnia and mood, which depended on age, gender, bipolar subtype, and a history of rapid cycling.

conclusionsOur results highlight the importance of monitoring sleep in people with BD. However, researchers and clinicians investigating the association between sleep and mood should consider subgroup differences in this relationship. Advances in digital technology mean that intensive longitudinal data on sleep and mood are becoming increasingly available. Novel methods to analyse these data present an exciting opportunity for furthering our understanding of BD.

Indexed as

Bipolar DisorderSleep Initiation and Maintenance DisordersAffectHumansLongitudinal StudiesSleepAutoregressive effectbipolar disorderdepressionDSEMdynamic structural equation modellinginsomniaintensive longitudinal datamaniaMplussleep

Identifiers

PMID35074035
PMCPMC10277721
OpenAlexW4210510186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.