ArticleDiabetology & metabolic syndrome2022
Frequency of obesity and metabolic syndrome in childhood leukemia and lymphoma survivors.
Article in Diabetology & metabolic syndrome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Factors impacting physical activity among post-treatment pediatric cancer survivors with overweight and obesity.European journal of pediatrics · 2024Trial
- Excess body weight at diagnosis is associated with inferior ALL outcomes in male adolescents in the ALL-BFM 2000 study.Blood neoplasia · 2026Article
- Exploring Two Decades of Cancer Trends in Adolescents and Young Adults: Insights From a Resource-Restricted Country.World journal of oncology · 2026Article
- Adipose tissue: an overlooked target of medical ionizing radiation and its metabolic consequences.Frontiers in public health · 2026Review
- Pretreatment TyG-BMI predicts CD19 CAR-T persistence and prognosis in diffuse large B-cell lymphoma.Frontiers in oncology · 2026Article
- Exploring childhood cancer survivor, parent, healthcare and community professionals' experiences of, and priorities for, using digital health to engage in physical activity: a mixed methods study.Journal of cancer survivorship : research and practice · 2025Article
- [High glucose levels in children at diagnosis of acute lymphoblastic leukemia].Revista medica del Instituto Mexicano del Seguro Social · 2025Observational
- Body composition changes in pediatric patients with lymphoma after chemotherapy: a retrospective study.European journal of pediatrics · 2025Observational
- Glycated albumin may have a complementary role to glycated hemoglobin in glucose monitoring in childhood acute leukemia.Annals of pediatric endocrinology & metabolism · 2024Article
- Abnormal HDL lipid and protein composition following pediatric cancer treatment: an associative study.Lipids in health and disease · 2023Article
- Application Value of Metagenomics Next-Generation Sequencing (mNGS) in Detection of Mucormycosis after Chemotherapy in Childhood Acute Leukemia.Evidence-based complementary and alternative medicine : eCAM · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIn this study, it was aimed to determine the prevalence and clinical features of obesity and metabolic syndrome, which are long-term effects of survivors after treatment in children with leukemia and lymphoma. PATIENTS AND
methodsPatients with leukemia and lymphoma, who were diagnosed between 2000 and 2012 (at least 2 two years after remission) were included. Data obtained through reviewing the family history, demographic characteristics, anthropometric measurements, and laboratory parameters (blood glucose, lipid, and insulin levels) were analyzed and compared at the time of diagnosis, after the treatment and at time of the study.
resultsEighty nine patients (45 boys, 44 girls) were included (mean age: 14.7 ± 4.3 years): 77.5% had acute lymphoblastic leukemia, 11.2% had acute myeloid leukemia, and 11.2% had lymphoma. Overall, 46% patients had received radiotherapy, 7% had undergone surgery, and 2.2% had received stem cell transplantation in addition to chemotherapy. The mean duration of treatment was 2.4 years, and the time elapsed after treatment was 4.9 years. While only one had obesity at the diagnosis, a significant increase in obesity (20%), hypertension (15.7%), hyperglycemia (15%), insulin resistance (35%) were observed at the time of study, and family history of hypertension, dyslipidemia, and cardiovascular diseases were significantly higher in this subgroup.
conclusionThe prevalence of metabolic syndorme is higher in children with leukemia and lymphoma after treatment, and begins to increase with the initiation of treatment and continues to increase over time. These children should be followed-up for late-effects including metabolic syndrome through life-long period.
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