Evidence map›Paper›PMID 35073944›Full record

ArticleItalian journal of pediatrics2022

Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound.

Noemi Graziano, Carlo Agostoni, Francesca Chiaraviglio, Céline Betti, Arianna Piffer, Mario G Bianchetti, Gregorio P Milani

Open access · goldAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Noemi GrazianoDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Carlo AgostoniDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy. carlo.agostoni@unimi.it.ORCID http://orcid.org/0000-0002-5006-0832
Francesca ChiaraviglioFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Radiology Unit, Milan, Italy.
Céline BettiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Radiology Unit, Milan, Italy.
Arianna PifferPediatric Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
Mario G BianchettiPediatric Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Switzerland.
Gregorio P MilaniDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale San Giovanni Bellinzona · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. CASES PRESENTATION: Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities.

conclusionsKidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice.

Indexed as

HypoaldosteronismPyelonephritisUrinary TractUrinary Tract InfectionsChildFemaleHumansInfantMaleUltrasonographyAcidosisAldosterone; children; infantsHyponatremiaInfectionPyelonephritisSonography

Identifiers

PMID35073944
PMCPMC8785504
OpenAlexW4207063843

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.