SynthesisEuropean geriatric medicine2022
Mortality and complication rates in nonagenarians and octogenarians undergoing total hip and knee arthroplasty: a systematic review and meta-analysis.
Synthesis in European geriatric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Surgical urgency and outcomes in nonagenarian and centenarian patients admitted to the ICU after hip replacement: a binational multicenter cohort study.Trauma surgery & acute care open · 2026Article
- Total knee arthroplasty in patients with degenerative spine disease: does spinal fusion affect outcomes? A matched comparative analysis using a national database.Knee surgery & related research · 2025Article
- A Nomogram Model for Predicting Prolonged Postoperative LOS After Total Knee Arthroplasty in Osteoarthritis Patients.Clinical interventions in aging · 2025Article
- Does a Specific Sequential Combination of Antiseptic Solutions for Chemical Debridement in Periprosthetic Joint Infection Improve Outcomes vs. Solution Alone? An In Vivo Study.Antibiotics (Basel, Switzerland) · 2024Article
- The Perioperative NonaGEnaRIan And cenTenarian suRgICal (GERIATRIC) Risk Stratification Tool.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Patient-Centered Discharge and Postoperative Length of Hospital Stay in Primary Total Knee Arthroplasty.Cureus · 2024Article
- Surgical management of spinal pathologies in the octogenarian: a narrative review.GeroScience · 2024Review
- An In Vitro Study to Assess the Best Strategy for the Chemical Debridement of Periprosthetic Joint Infection.Antibiotics (Basel, Switzerland) · 2023Article
- A Comparative Analysis of Perioperative Complications in Octogenarians and Patients under 60 Years of Age after Primary Cemented Total Knee Arthroplasty.Clinical medicine & research · 2023Article
- The risk analysis of perioperative complications of cementless hip arthroplasty in octogenarians.Archives of orthopaedic and trauma surgery · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdvancing age is a significant risk factor for the development of perioperative complications and mortality in patients undergoing total hip or knee arthroplasty (THA or TKA) due to their compromised health status and the associated medical comorbidities. The purpose of this review is to identify if nonagenarians having a THA or TKA are associated with a higher incidence of mortality and morbidity compared to octogenarians.
methodsMedline, Scopus, and the Cochrane library were searched for relevant studies. The primary outcome of the review was the incidence of mortality. The secondary outcomes were the 30-day readmission, the perioperative complications, and the length of hospital stay (LOS).
resultsSix studies with 479,630 patients were included in the review. No difference between nonagenarians and octogenarians was detected regarding the in-hospital mortality, the 30-day readmission rate, and the LOS. However, nonagenarians were associated with a greater 1-year mortality rate (OR: 2.4; 95% CI 1.91-3.01, P < 0.001; I
conclusionAlthough nonagenarians undergoing TKA or THA can achieve the same clinical benefit as octogenarians, they have a higher risk of perioperative complications and 1-year mortality. Therefore, meticulous preoperative screening, proper patient selection and optimization of comorbidities are essential to minimize any postoperative side effects in patients over 90 years of age.
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