SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022
The impact of loneliness and social isolation on health state utility values: a systematic literature review.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- An Updated Systematic Literature Review of the Economic Costs of Loneliness and Social Isolation and the Cost Effectiveness of Interventions.PharmacoEconomics · 2025Pooled it
- Investigating relationships between loneliness, social isolation and health.Nature communications · 2026Article
- Measuring outcomes for loneliness research: examining the appropriateness of the EQ-5D-5 L and EQ-HWB.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Personal online social networks as moderators of the association between loneliness and quality of life in Polish adults aged 50.Scientific reports · 2025Article
- Improvement in quality of life and loneliness after the community connections program: a community-based pilot intervention in South Australia.BMC psychology · 2025Article
- Disutility associated with social isolation and loneliness in Germany: results of a population survey using the EQ-5D-5L instrument.Health and quality of life outcomes · 2024Article
- Perceptions of inequality and loneliness as drivers of social unraveling: Evidence from South Korea.Scientific reports · 2024Article
- Experiences of Social Isolation and Loneliness in Chronic Kidney Disease: A Secondary Qualitative Analysis.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
- [Migration background and loneliness among middle-aged and older adults in Germany].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024Article
- A Systematic Review of Artificial Intelligence Used to Predict Loneliness, Social Isolation, and Drug Use During the COVID-19 Pandemic.Journal of multidisciplinary healthcare · 2024Review
- Extending the EQ-5D: the case for a complementary set of 4 psycho-social dimensions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- The effects of social isolation stress and discrimination on mental health.Translational psychiatry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLoneliness and social isolation are recognised as social problems and denote a significant health burden. The aim of this study was to conduct a systematic literature review to explore the health state utility values (HSUVs) associated with loneliness and/or social isolation.
methodPeer-reviewed journals published in English language that reported both HSUVs along with loneliness and/or social isolation scores were identified through five databases. No restrictions were made relating to the population, study design or utility estimation method used.
resultsIn total, 19 papers were included; 12 included a measure of loneliness, four studies included a measure of social isolation and three studies considered both loneliness and social isolation. All studies focused on individuals with pre-existing health conditions-where the EQ-5D-3L instrument was most frequently used to assess HSUVs. HSUVs ranged from 0.5 to 0.95 in those who reported not being lonely, 0.42 to 0.97 in those who experienced some level of loneliness, 0.3 to 0.87 in those who were socially isolated and 0.63 to 0.94 in those who were not socially isolated.
conclusionThere was significant variation in HSUVs complicated by the presence of co-morbidities, population heterogeneity, variations in methods used to derive utility scores and differences in the measurement of loneliness and/or social isolation. Nevertheless, the lower HSUVs observed should be considered to significantly impact quality of life, though we also note the need for further research to explore the unique impact of loneliness and social isolation on HSUVs that can be used in the future economic evaluations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.