Evidence map›Paper›PMID 35072832›Full record

ArticleArchives of osteoporosis2022

Assessment of calcium and vitamin D medications adherence in patients with hypoparathyroidism after thyroidectomy.

Muhammet Cuneyt Bilginer, Cevdet Aydin, Burcak Polat, Sevgul Faki, Oya Topaloglu, Reyhan Ersoy, Bekir Cakir

Abstract read
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In one paragraph

Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. A delicate balance: the challenges of hypoparathyroidism.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammet Cuneyt BilginerFaculty of Medicine, Department of Endocrinology and Metabolism, Karadeniz Technical University, Trabzon, Turkey. cuneytbilginer@hotmail.com.
Cevdet AydinFaculty of Medicine, Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Burcak PolatFaculty of Medicine, Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Sevgul FakiDepartment of Endocrinology and Metabolism, University of Health Sciences Turkey, Ankara City Hospital, Ankara, Turkey.
Oya TopalogluFaculty of Medicine, Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Reyhan ErsoyFaculty of Medicine, Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University, Ankara, Turkey.
Bekir CakirFaculty of Medicine, Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we found that patients with hypoparathyroidism had a problem with calcium medication compliance, and this problem increased with the duration of the disease. We also showed that patients are concerned about the possible side effects of drugs.

introductionIn this study, we aimed to evaluate adherence to active vitamin D and calcium replacement in patients with post-surgical hypoparathyroidism.

methodsTo elucidate the medication adherence, we performed a questionnaire survey using the six-item "Medication adherence questionnaire"(MAQ). The first, second, and sixth questions reflect the motivation status of the patients whereas the third, fourth, and fifth questions reflect the knowledge about the medication that is received. The responses are scored and patients are classified regarding their motivation to and knowledge about the particular drug.

resultsTotally, 64 patients (male: 12/female: 52; mean age 48.6±11.6 years) who had post-operative hypoparathyroidism were included in our study. Median disease durance was 60 months (min-max: 12-295 months). We found that motivation score of calcium usage was significantly lower compared to vitamin D usage (p<0.001). The calcium motivation score was reversely correlated with disease duration (r= -0.256 and p=0.046). The most common worry about calcium usage was nephrotoxicity, and the most common worries about calcitriol treatment were kidney damage and polyuria. One-third of the patients were taking oral calcium and calcitriol less than the recommended dose.

conclusionOne-third of patients lack motivation to use calcium whereas half of the patients experiences anxiety about drug-related side effects. This is a preliminary study showing that vital calcium and active vitamin D intake may be interrupted due to side effect anxiety.

Indexed as

CalciumHypoparathyroidismAdultFemaleHumansMaleMedication AdherenceMiddle AgedThyroidectomyVitamin DCalciumVitamin DCalciumHypoparathyroidismMedications adherencePatient complianceVitamin D

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.