ArticleJournal of materials science. Materials in medicine2022
Chitosan-collagen-hydroxyapatite membranes for tissue engineering.
Article in Journal of materials science. Materials in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Effect of addition of hydroxyapatite nanofibers to glass ionomer cement on fracture toughness, microhardness, and fluoride release.Odontology · 2026Article
- Electrospun Chitosan/Collagen Fibers Incorporating PLGA and Hydroxyapatite Nanoparticles for In-Vitro 3T3 Fibroblast Migration.Polymers · 2026Article
- Article
- Biomimetic Scaffold of Chitosan fromAdvanced pharmaceutical bulletin · 2026Article
- Calcium Phosphate Nanostructured Biocomposites with Applications in Bone Tissue Engineering.Materials (Basel, Switzerland) · 2026Review
- Bioprinting in Tissue Repair and Its ENT Applications.Polymers · 2026Review
- Effect of incorporating chitosan/hydroxyapatite composite nanoparticles into a universal adhesive on bonding efficacy to caries-affected dentin and bioactivity.BMC oral health · 2026Article
- Synthesis and Characterization of a Marine Collagen-Chitosan/HA-SiOGels (Basel, Switzerland) · 2026Article
- Biocompatible protein-nanomaterial scaffolds for controlled drug delivery.RSC advances · 2026Article
- Simultaneous synthesis of hydroxyapatite/chitosan composite from crab shells and its polycaprolactone-blended scaffolds for enhanced bone regeneration.RSC advances · 2025Article
- Development of injectable cuttlebone derived nanohydroxyapatite hydrogel for osteoblast cell encapsulation.Biochemistry and biophysics reports · 2025Article
- Three-Dimensional Printed Hybrid Scaffolds with Layered Polycaprolactone/Nanosized Smectic Clay Nanocomposite and Chitosan/Collagen/Demineralized Bone Powder Hydrogels Targeting Osteochondral Tissue Engineering.Journal of functional biomaterials · 2025Article
- Thermally Conductive Biopolymers in Regenerative Medicine and Oncology: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Sea CucumberMarine drugs · 2025Article
- Influence of Scaffold Structure and Biomimetic Properties on Adipose Stem Cell Homing in Personalized Reconstructive Medicine.Biomimetics (Basel, Switzerland) · 2025Review
- Collagen-Chitosan Composites Enhanced with Hydroxytyrosol for Prospective Wound Healing Uses.Pharmaceutics · 2025Article
- Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus.Journal of materials science. Materials in medicine · 2025Article
- Biomembranes Based on Potato Starch Modified by Dry Heating Treatment: One Sustainable Strategy to Amplify the Use of Starch as a Biomaterial.Biomacromolecules · 2025Article
- Enhancing Thin Film Properties of Chitosan-Collagen Biocomposites Through Potassium Silicate and Tannic Acid Integration.Polymers · 2025Article
- Challenges and Innovations in Alveolar Bone Regeneration: A Narrative Review on Materials, Techniques, Clinical Outcomes, and Future Directions.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue engineering is growing in developing new technologies focused on providing effective solutions to degenerative pathologies that affect different types of connective tissues. The search for biocompatible, bioactive, biodegradable, and multifunctional materials has grown significantly in recent years. Chitosan, calcium phosphates collagen, and their combination as composite materials fulfill the required properties and could result in biostimulation for tissue regeneration. In the present work, the chitosan/collagen/hydroxyapatite membranes were prepared with different concentrations of collagen and hydroxyapatite. Cell adhesion was evaluated by MTS assay for two in vitro models. Additionally, cytotoxicity of the different membranes employing hemolysis of erythrocytes isolated from human blood was carried out. The structure of the membranes was analyzed by X-rays diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermal stability properties by thermogravimetric methods (TGA). The highest cell adhesion after 48 h was obtained for chitosan membranes with the highest hydroxyapatite and collagen content. All composite membranes showed good cell adhesion and low cytotoxicity, suggesting that these materials have a significant potential to be used as biomaterials for tissue engineering. Graphical abstract.
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Registered trials
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