Evidence map›Paper›PMID 35072780›Full record

ArticleJournal of bone and mineral metabolism2022

Bone markers and bone mineral density associates with periodontitis in females with poly-cystic ovarian syndrome.

Afaf Zia, S Hakim, A U Khan, A Bey, H Ateeq, S Parveen, S Khalid, Fnk Yusufi

Abstract read
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Article in Journal of bone and mineral metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Afaf ZiaDepartment of Periodontics and Community Dentistry, Dr. Ziauddin Ahmed Dental College (DRZADC), Aligarh Muslim University (AMU), Aligarh, 202002, Uttar Pradesh, India. afafzia@gmail.com.ORCID http://orcid.org/0000-0003-2932-4909
S HakimDepartment of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College and Hospital (JNMCH), AMU, Aligarh, Uttar Pradesh, India.
A U KhanInterdisciplinary Biotechnology Unit, AMU, Aligarh, Uttar Pradesh, India.
A BeyDepartment of Periodontics and Community Dentistry, Dr. Ziauddin Ahmed Dental College (DRZADC), Aligarh Muslim University (AMU), Aligarh, 202002, Uttar Pradesh, India.
H AteeqDepartment of Biochemistry, AMU, Aligarh, Uttar Pradesh, India.
S ParveenDepartment of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College and Hospital (JNMCH), AMU, Aligarh, Uttar Pradesh, India.
S KhalidInterdisciplinary Biotechnology Unit, AMU, Aligarh, Uttar Pradesh, India.
Fnk YusufiDepartment of Statistics and Operations, AMU, Aligarh, Uttar Pradesh, India.
Aligarh Muslim University · INJawaharlal Nehru Medical College Hospital · IN

Funding

science and engineering research board SERB (Govt of India) ECR2016/001632
6 · The paper itself

Abstract

introductionStudies suggest an association between poly-cystic ovarian syndrome (PCOS) and chronic periodontitis (CP), both being inflammatory conditions. However, insufficient evidence assesses the impact of this inflammation on bone metabolism and bone turnover markers (BTMs). The present study aimed to determine the association between BTMs, bone mineral density (BMD), and clinical periodontal parameters in PCOS women with CP. MATERIALS AND

methodsThree groups, each with 40 newly diagnosed (1) PCOS+CP, (2) PCOS alone, (3) CP alone, and fourth group (n = 20) systemically and periodontally healthy females aged 18-30 years were included in the study. Full mouth clinical periodontal parameters, C-terminal telopeptides of type I collagen (CTX), bone alkaline phosphatase (ALP), BMD and 25-hydroxyvitamin D (VD) were recorded for all.

resultsLow BMD (0.89 ± 0.11 g/cm

conclusionEnhanced inflammatory thrust by periodontitis increases CTX levels and decreases bone ALP and BMD levels in women with PCOS. Screening PCOS women for periodontal disease and vice versa may have a direct bearing on overall bone health.

Indexed as

PeriodontitisPolycystic Ovary SyndromeAlkaline PhosphataseBiomarkersBone DensityBone RemodelingCollagen Type ICross-Sectional StudiesFemaleHumansAlkaline PhosphataseBiomarkersCollagen Type IBiomarkersBone biologyEndocrinologyOral-systemic diseasesPeriodontal diseases

Identifiers

PMID35072780
OpenAlexW4207030917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.