Evidence map›Paper›PMID 35072738›Full record

SynthesisWorld journal of urology2022

Role of pre-operative ureteral stent on outcomes of retrograde intra-renal surgery (RIRS): systematic review and meta-analysis of 3831 patients and comparison of Asian and non-Asian cohorts.

Y X T Law, J Y C Teoh, D Castellani, E J Lim, E O T Chan, M Wroclawski, G M Pirola, C Giulioni, E Rubilotta, M Gubbioti and 5 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 7 countries.

Y X T LawDepartment of Urology, National University Hospital, National University Health System, Singapore, Singapore. terencelaw83@gmail.com.ORCID http://orcid.org/0000-0002-5277-7511
J Y C TeohS.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
D CastellaniUrology Division, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Università Politecnica Delle Marche, Ancona, Italy.
E J LimDepartment of Urology, Singapore General Hospital, Singapore, Singapore.
E O T ChanS.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
M WroclawskiDepartment of Urology, Hospital Israelita Albert Einstein, São Paulo, Brazil.
G M PirolaDepartment of Urology, San Donato Hospital, Arezzo, Italy.
C GiulioniUrology Division, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Università Politecnica Delle Marche, Ancona, Italy.
E RubilottaDepartment of Urology, A.O.U.I. Verona University, Verona, Italy.
M GubbiotiDepartment of Urology, San Donato Hospital, Arezzo, Italy.
S ScarcellaUrology Division, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Università Politecnica Delle Marche, Ancona, Italy.
B H ChewDepartment of Urologic Sciences, University of British Columbia, Vancouver, Canada.
O TraxerService d'Urologie, Sorbonne Université, Paris, France.
B K SomaniDepartment of Urology, University Hospital Southampton NHS Trust, Southampton, UK.
V GauharDepartment of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.
Ospedali Riuniti di Ancona · ITChinese University of Hong Kong · HKOspedale San Donato · ITHospital Israelita Albert Einstein · BRNational University Hospital · SGNg Teng Fong General Hospital · SGSingapore General Hospital · SGSorbonne Université · FRUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of British Columbia · CAUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the outcomes of pre-stented (PS) versus non-pre-stented (NPS) patients who have undergone retrograde intrarenal surgery (RIRS) for renal calculi with subgroup analysis of Asian and non-Asian cohorts.

methodsProtocol is registered in PROSPERO, CRD42021261123. Eligible studies identified from four electronic databases. Meta-analysis was done to enumerate the outcomes of RIRS in between PS and NPS. Secondary sub-analysis was done to look for differences in outcomes in Asian and non-Asian cohorts.

resultsFourteen studies involving 3831 patients (4 prospective, 10 retrospective studies) were included. PS patients experienced higher success rates of ureteral access sheath (UAS) insertion than NPS (RR 1.09, 95% CI 1.05-1.13, p < 0.00001). PS patients had lower risk of ureteral injuries from UAS placement (RR 0.69, 95% CI 0.50-0.96, p = 0.03). No significant differences in intra- and postoperative complications between two groups were found. Stone-free rate (SFR) outcomes for residual fragment (RF) cut-off of < 1 mm and < 4 mm favoured the PS patients (RR 1.10, 95% CI 1.04-1.17, p = 0.002 for < 4 mm, RR1.10, 95% CI 1.02-1.19, p = 0.02 for < 1 mm). In the subgroup analysis, PS Asian patients had similar SFR as NPS patients for SFR(< 4 mm) but non-Asian population showed better outcomes in the PS patients for SFR(< 4 mm) (RR 1.31, 95% CI 1.13-1.52, p = 0.0005).

conclusionsThis meta-analysis suggests that pre-stenting results in a higher success for UAS placement, minimising intraoperative ureteric injury, with higher overall SFR for any RF cut-off in PS cohorts. In non-Asian cohort, significant differences occurred at SFR < 4 mm but not for SFR < 1 mm. No difference was seen in our Asian cohort for any SFR cut-off in both PS and NPS patients.

Indexed as

Kidney CalculiUreterHumansProspective StudiesRetrospective StudiesStentsTreatment OutcomeAsianKidney calculiMeta-analysisOutcome studiesRetrograde intra-renal surgeryStent

Identifiers

PMID35072738
OpenAlexW4206956255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.