Evidence map›Paper›PMID 35072176›Full record

ArticleInterventional pulmonology (Middletown, Del.)2021

Potential enhanced association between obstructive lung disease and history of depression in patients with diabetes.

Maria E Ramos-Nino, Charles D MacLean, Benjamin Littenberg

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Interventional pulmonology (Middletown, Del.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Maria E Ramos-NinoSt. George's University, Department of Microbiology, Immunology, and Pharmacology, Grenada, West Indies.
Charles D MacLeanDepartment of Medicine, University of Vermont, Burlington, Vermont 05401, USA.
Benjamin LittenbergDepartment of Medicine, University of Vermont, Burlington, Vermont 05401, USA.
University of Vermont · US

Funding

Vermont Diabetes Information SystemR01DK061167 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI LITTENBERG, BENJAMIN · 2002 to 2005
$2.0M
Barriers to Optimum Diabetes OutcomesK24DK068380 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI LITTENBERG, BENJAMIN · 2004 to 2008
$790k
NIDDK NIH HHS K24 DK068380NIDDK NIH HHS R01 DK061167
6 · The paper itself

Abstract

backgroundDepression is one of the most common comorbidities of chronic diseases including diabetes and obstructive lung diseases (emphysema, chronic bronchitis, and asthma). Obstructive lung diseases and depression have few symptoms in common. However, they are both common in adults and associated with chronic inflammation. It is not clear if their coappearance in diabetic patients is coincidental or associated beyond that expected by chance.

methodsA total of 1,003 adults with diabetes in community practice settings were interviewed at home at the time of their enrolment into the Vermont Diabetes Information System, a clinical decision support program. Patients self-reported their personal and clinical characteristics, including any obstructive lung disease. Laboratory data were obtained directly from the clinical laboratory, and current medications were obtained by direct observation of medication containers. We performed a cross-sectional analysis of the interviewed subjects to assess a possible association between the prevalence of obstructive lung disease and depression.

resultsIn a multivariate logistic regression model, obstructive lung disease was significantly associated with depression even after correcting for gender, obesity (≥30 kg/m

conclusionThese data suggest a potential enhanced association between obstructive lung disease and depression in patients with diabetes. Future studies are needed to identify if inflammation is implicated in this association as a common denominator.

Indexed as

AsthmaCOPDDepressionDiabetesObstructive lung disease

Identifiers

PMID35072176
PMCPMC8783552
OpenAlexW4207094172

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.