Evidence map›Paper›PMID 35072031›Full record

ReviewCJC open2022

Short-term and Long-term Risk of Stroke in Patients With Perioperative Atrial Fibrillation After Cardiac Surgery: Systematic Review and Meta-analysis.

Michael K Wang, Pascal B Meyre, Rachel Heo, P J Devereaux, Lauren Birchenough, Richard Whitlock, William F McIntyre, Yu Chiao Peter Chen, Muhammad Zain Ali, Fausto Biancari and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CJC open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael K WangDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Pascal B MeyreDivision of Cardiology and Basel Cardiovascular Research Institute, Basel University Hospital, Basel, Switzerland.
Rachel HeoMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
P J DevereauxDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Lauren BirchenoughFaculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Richard WhitlockPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
William F McIntyreDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Yu Chiao Peter ChenDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Muhammad Zain AliSchool of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Fausto BiancariClinica Montevergine, GVM Care & Research, Mercogliano, Italy.
Jawad Haider ButtDepartment of Cardiology, Rigshopitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Jeff S HealeyDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Emilie P Belley-CôtéDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Andre LamyPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
David ConenDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative atrial fibrillation (POAF) after cardiac surgery has been associated with an increased risk of stroke in some studies. However, the exact magnitude of this association during short-term and long-term follow-up remains unclear.

methodsWe searched PubMed, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) for the time period from database inception to October 2020. We included observational studies with ≥ 100 patients that reported data on short-term or long-term stroke risk in patients with and without POAF after cardiac surgery. Data were pooled using random-effects models. We reported summary risk ratios (RRs) for studies reporting multivariable adjusted results and calculated absolute risk differences (ARDs) with 95% confidence intervals (CIs).

resultsA total of 55 studies with 540,209 patients were included. POAF was associated with both an increased relative risk (RR 1.69; 95% CI, 1.41-2.03; I

conclusionsPOAF after cardiac surgery was associated with an increased risk of both short-term and long-term stroke. However, the long-term stroke ARD was small, and whether these patients will benefit from long-term oral anticoagulation therapy is unclear.

Identifiers

PMID35072031
PMCPMC8767142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.